A confusion of pathways: Discerning cell death mechanisms in SARS-CoV-2 infection

被引:0
|
作者
Wong, Lok-Yin Roy [1 ,2 ]
Perlman, Stanley [3 ,4 ]
机构
[1] Rutgers New Jersey Med Sch, Ctr Virus Host Innate Immun, Newark, NJ 07103 USA
[2] Rutgers New Jersey Med Sch, Dept Microbiol Biochem & Mol Genet, Newark, NJ 07103 USA
[3] Univ Iowa, Dept Microbiol & Immunol, Iowa City, IA 52242 USA
[4] Univ Iowa, Dept Pediat, Iowa City, IA 52242 USA
关键词
D O I
10.1126/sciimmunol.adp8170
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Upon SARS-CoV-2 infection, infected cells undergo necroptosis, whereas delayed apoptosis and pyroptosis occur in uninfected, bystander cells, thus providing a plausible explanation for the extensive injury among myriad uninfected cells.
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