Photoredox-catalyzed C(sp2)-H trifluoromethylation of 3-methylene-isoindolin-1-ones under metal-free conditions

被引：0
|
作者：
Zhou, Yuan-Xia [1 ]
Liu, Feng-Qian [1 ]
Wang, Guo-Qin [1 ]
Yang, Dan [1 ]
Han, Pan [1 ]
Jing, Lin-Hai [1 ]
机构：
[1] China West Normal Univ, Coll Chem & Chem Engn, Chem Synth & Pollut Control Key Lab Sichuan Prov, Nanchong 637002, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2024年 / 22卷 / 34期
关键词：
GENERATION;
D O I：
10.1039/d4ob01046a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile synthetic method for direct C(sp(2))-H bond trifluoromethylation of 3-methylene-isoindolin-1-ones under visible-light-induced metal-free conditions is presented. This protocol features mild reaction conditions, broad substrate scope and excellent functional group tolerance, resulting in a range of structurally diverse trifluoromethylated products in good to excellent yields.
引用
收藏
页码：6928 / 6932
页数：5
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