Diabetic Retinopathy - Pathophysiology to Treatment: A Review

被引：2

作者：

Singh, Randhir ^{[1
,2
]}

Walia, Aditya ^{[3
]}

Kaur, Jasleen ^{[3
]}

Kumar, Praveen ^{[4
]}

Verma, Inderjeet ^{[5
]}

Rani, Nidhi ^{[3
]}

机构：

[1] Cent Univ Punjab, Dept Pharmacol, Bathinda, Punjab, India

[2] Graph Era Hill Univ, Dept Pharm, Dehra Dun, India

[3] Chitkara Univ, Chitkara Coll Pharm, Chitkara, Punjab, India

[4] SunPharma, PO Barotiwala, Solan 174103, Himachal Prades, India

[5] Maharishi Markandeshwar Deemed Univ, MM Coll Pharm, Ambala, Haryana, India

来源：

CURRENT DIABETES REVIEWS | 2025年 / 21卷 / 03期

关键词：

Diabetic retinopathy; pathogenesis; microvascular changes; inflammation; diabetes; neurodegeneration; DEXAMETHASONE IMPLANT; OXIDATIVE STRESS; PERICYTE LOSS; IN-VITRO; RANIBIZUMAB; APOPTOSIS; ACTIVATION; RETINA; ANTIOXIDANT; CATARACT;

D O I：

10.2174/0115733998259940231105200251

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Diabetic retinopathy (DR) is a microvascular disease affecting the eyes of diabetic patients, and is the most prevalent complication of diabetes mellitus. Vision improvement is not possible in the majority of DR patients. Several studies have indicated that microvascular changes, inflammation, oxidative stress, and retinal neurodegeneration are involved in the pathogenesis of DR. Therefore, there is an urgent need for the development of new and effective treatment for DR. Understanding the molecular mechanisms involved in the pathogenesis of disease will pave a way for better treatment and management of DR. This article has emphasized the molecular pathogenesis and treatment of DR.

引用

页数：10

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