Clove essential oil and its major component, eugenol: a comparative study of their in vitro antioxidant and anticancer properties

被引：0
|
作者：
Haro-Gonzalez, Jose Nabor [1 ]
Barbosa-Nunez, Jorge Alejandro [1 ]
Castillo-Herrera, Gustavo Adolfo [1 ]
Estarron-Espinosa, Mirna [1 ]
Herrera-Rodriguez, Sara Elisa [2 ]
Espinosa-Andrews, Hugo [1 ]
Alvarez, Angel H. [3 ]
Martinez-Velazquez, Moises [3 ]
机构：
[1] Ctr Invest & Asistencia Tecnol & Diseno Estado Jal, Unidad Tecnol Alimentaria, Zapopan, Jalisco, Mexico
[2] Ctr Invest & Asistencia Tecnol & Diseno Estado Jal, Unidad Sureste, Merida, Yucatan, Mexico
[3] Ctr Invest & Asistencia Tecnol & Diseno Estado Jal, Unidad Biotecnol Med & Farmaceut, Guadalajara, Jalisco, Mexico
来源：
NATURAL PRODUCT RESEARCH | 2024年
关键词：
Clove essential oil; eugenol; anticancer activity; antioxidant; Syzygium aromaticum L; DPPH; total phenolic content; CHEMICAL-COMPOSITION;
D O I：
10.1080/14786419.2024.2404658
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Syzygium aromaticum L. (clove) is a species native to subtropical countries. Its dried flower buds are rich in essential oils, which have shown insecticidal, anti-inflammatory and anaesthetic effects. This work was aimed to study the differences in antioxidant and anticancer activities between clove essential oil (CEO) and its major component, eugenol. The chemical composition of the CEO was determined by GC-MS. The physicochemical properties and antioxidant activity were determined in CEO and eugenol. Finally, anticancer activities were assayed against seven cell lines. Chemical analysis revealed that 80% of the CEO was eugenol. The density and IR were similar, and the colour was Delta E*>3. CEO had a lower phenolic content, but similar antioxidant activity to eugenol. The anticancer activity of the CEO was greater than that of eugenol in all the cell lines except for HeLa cells. These results suggest that secondary compounds in CEO enhance its antioxidant and anticancer activities.
引用
收藏
页数：8
相关论文
共 50 条
  • [31] Bio-molluscicidal potential and biochemical mechanisms of clove oil and its main component eugenol against the land snail, Theba pisana
    Gad, Amira F.
    Abdelgalil, Gaber M.
    Radwan, Mohamed A.
    PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 2023, 192
  • [32] Optimization of preparation process of β-cyclodextrin inclusion compound of clove essential oil and evaluation of heat stability and antioxidant activities in vitro
    Shasha Ma
    Zhenyu Zhao
    Pinghuai Liu
    Journal of Food Measurement and Characterization, 2018, 12 : 2057 - 2067
  • [33] Chitosan-Oxidized Pullulan Hydrogels Loaded with Essential Clove Oil: Synthesis, Characterization, Antioxidant and Antimicrobial Properties
    Suflet, Dana Mihaela
    Constantin, Marieta
    Pelin, Irina Mihaela
    Popescu, Irina
    Rimbu, Cristina M.
    Horhogea, Cristina Elena
    Fundueanu, Gheorghe
    GELS, 2024, 10 (04)
  • [34] Evaluation of Essential Oil Components in Genetically Modified Poaceae Plants: A Comparative Study of Their Whitening and Antioxidant Activities In Vitro
    Huang, Wei-Hsiang
    Tsai, Feng-Jie
    Ho, Tse-Tsung
    Lin, Chih-Chien
    RECORDS OF NATURAL PRODUCTS, 2024,
  • [35] Cytotoxic and antioxidant properties of essential oil of Centaurea behen L. in vitro
    Celikezen, Fatih Caglar
    Hayta, Sukru
    Ozdemir, Ozlem
    Turkez, Hasan
    CYTOTECHNOLOGY, 2019, 71 (01) : 345 - 350
  • [36] Kinetic Study of Cumin Essential Oil and of its Major Components
    Benrejdal, A.
    Dridi, F.
    Nabiev, M.
    Benyoussef, E. -H.
    ASIAN JOURNAL OF CHEMISTRY, 2012, 24 (05) : 1952 - 1954
  • [37] Cytotoxic and antioxidant properties of essential oil of Centaurea behen L. in vitro
    Fatih Çağlar Çelikezen
    Şükrü Hayta
    Özlem Özdemir
    Hasan Türkez
    Cytotechnology, 2019, 71 : 345 - 350
  • [38] Evaluation of anticancer, antimicrobial, and antioxidant activities of rosemary (Rosmarinus Officinalis) essential oil and its Nanoemulgel
    Eid, Ahmad M.
    Jaradat, Nidal
    Issa, Linda
    Abu-Hasan, Aya
    Salah, Nada
    Dalal, Mohamad
    Mousa, Ahmed
    Zarour, Abdalraziq
    EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE, 2022, 55
  • [39] In vitro antimycoplasmal activity of citrus bergamia essential oil and its major components
    Furneri, Pio Maria
    Mondello, Luigi
    Mandalari, Giuseppina
    Paolino, Donatella
    Dugo, Paola
    Garozzo, Adriana
    Bisignano, Giuseppe
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 52 : 66 - 69
  • [40] In Vitro Inhibitory Effect of Clove Essential Oil and Its Two Active Principles on Tooth Decalcification by Apple Juice
    Marya, Charu M.
    Satija, Gunjan
    Avinash, J.
    Nagpal, Ruchi
    Kapoor, Rohtash
    Ahmad, Aijaz
    INTERNATIONAL JOURNAL OF DENTISTRY, 2012, 2012
12345