Clove essential oil and its major component, eugenol: a comparative study of their in vitro antioxidant and anticancer properties

被引：0
|
作者：
Haro-Gonzalez, Jose Nabor [1 ]
Barbosa-Nunez, Jorge Alejandro [1 ]
Castillo-Herrera, Gustavo Adolfo [1 ]
Estarron-Espinosa, Mirna [1 ]
Herrera-Rodriguez, Sara Elisa [2 ]
Espinosa-Andrews, Hugo [1 ]
Alvarez, Angel H. [3 ]
Martinez-Velazquez, Moises [3 ]
机构：
[1] Ctr Invest & Asistencia Tecnol & Diseno Estado Jal, Unidad Tecnol Alimentaria, Zapopan, Jalisco, Mexico
[2] Ctr Invest & Asistencia Tecnol & Diseno Estado Jal, Unidad Sureste, Merida, Yucatan, Mexico
[3] Ctr Invest & Asistencia Tecnol & Diseno Estado Jal, Unidad Biotecnol Med & Farmaceut, Guadalajara, Jalisco, Mexico
来源：
NATURAL PRODUCT RESEARCH | 2024年
关键词：
Clove essential oil; eugenol; anticancer activity; antioxidant; Syzygium aromaticum L; DPPH; total phenolic content; CHEMICAL-COMPOSITION;
D O I：
10.1080/14786419.2024.2404658
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Syzygium aromaticum L. (clove) is a species native to subtropical countries. Its dried flower buds are rich in essential oils, which have shown insecticidal, anti-inflammatory and anaesthetic effects. This work was aimed to study the differences in antioxidant and anticancer activities between clove essential oil (CEO) and its major component, eugenol. The chemical composition of the CEO was determined by GC-MS. The physicochemical properties and antioxidant activity were determined in CEO and eugenol. Finally, anticancer activities were assayed against seven cell lines. Chemical analysis revealed that 80% of the CEO was eugenol. The density and IR were similar, and the colour was Delta E*>3. CEO had a lower phenolic content, but similar antioxidant activity to eugenol. The anticancer activity of the CEO was greater than that of eugenol in all the cell lines except for HeLa cells. These results suggest that secondary compounds in CEO enhance its antioxidant and anticancer activities.
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页数：8
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