UGT-MEDIATED CLEARANCE IVIVE MAY BE IMPROVED USING RELATIVE ACTIVITY FACTOR APPROACH

被引：0
|
作者：
Shaikh, Sahil [1 ]
Patel, Mitesh [1 ]
Deshmukh, Sujal [1 ]
机构：
[1] Novartis Inst Biomed Res, Cambridge, MA USA
来源：
DRUG METABOLISM AND PHARMACOKINETICS | 2024年 / 55卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P92
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Investigation of MicroRNA and transcription factor mediated regulatory network for silicosis using systems biology approach
    Choudhari, J. K.
    Verma, M. K.
    Choubey, J.
    Sahariah, B. P.
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [32] Investigation of MicroRNA and transcription factor mediated regulatory network for silicosis using systems biology approach
    J. K. Choudhari
    M. K. Verma
    J. Choubey
    B. P. Sahariah
    Scientific Reports, 11
  • [33] Resolution of acyclovir-associated neurotoxicity with the aid of improved clearance estimates using a Bayesian approach: A case report and review of the literature
    Watson, W. A.
    Rhodes, N. J.
    Echenique, I. A.
    Angarone, M. P.
    Scheetz, M. H.
    JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2017, 42 (03) : 350 - 355
  • [34] Investigation of the Effects of Altered Receptor Binding Activity on the Clearance of Erythropoiesis-Stimulating Proteins: Nonerythropoietin Receptor-Mediated Pathways may Play a Major Role
    Agoram, Balaji
    Aoki, Ken
    Doshi, Sameer
    Gegg, Colin
    Jang, Graham
    Molineux, Graham
    Narhi, Linda
    Elliott, Steve
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2009, 98 (06) : 2198 - 2211
  • [35] Characterization of the metabolic contributions of cytochrome P450 isoforms to bicyclol using the relative activity factor method
    Luo, Li-jun
    Liu, Xiao
    Li, Yan
    Li, Yang
    Sheng, Li
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2024, 26 (08) : 918 - 929
  • [36] RELATIVE ACTIVITY FACTOR (RAF)-BASED SCALING OF UPTAKE CLEARANCE OF OATP1B SUBSTRATES FROM TRANSFECTED CELL SYSTEMS TO HUMAN HEPATOCYTES AND TO IN VIVO
    Izumi, Saki
    Nozaki, Yoshitane
    Komori, Takafumi
    Maeda, Kazuya
    Kusuhara, Hiroyuki
    Sugiyama, Yuichi
    DRUG METABOLISM AND PHARMACOKINETICS, 2019, 34 (01) : S19 - S19
  • [37] Impact of Probe Substrate Selection on Cytochrome P450 Reaction Phenotyping Using the Relative Activity Factor
    Siu, Y. Amy
    Lai, W. George
    DRUG METABOLISM AND DISPOSITION, 2017, 45 (02) : 183 - 189
  • [38] A novel pharmacological approach of herbal mediated cerium oxide and silver nanoparticles with improved biomedical activity in comparison with Lawsonia inermis
    Shanker, Kalakotla
    Naradala, Jayarambabu
    Mohan, G. Krishna
    Mydin, Rabiatul Basria S. M. N.
    Gupta, V. Ramamohan
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2019, 174 : 199 - 206
  • [39] improved approach for analysis of coupled structures in Energy Finite Element Analysis using the coupling loss factor
    Liu, Zhihui
    Niu, Junchuan
    Gao, Xiang
    COMPUTERS & STRUCTURES, 2018, 210 : 69 - 86
  • [40] Relative quantities of catalytically active CYP 2C9 and 2C19 in human liver microsomes: Application of the relative activity factor approach
    Venkatakrishnan, K
    von Moltke, LL
    Greenblatt, DJ
    JOURNAL OF PHARMACEUTICAL SCIENCES, 1998, 87 (07) : 845 - 853
12345