Muscular MRI and magnetic resonance neurography in spinal muscular atrophy

被引:0
|
作者
Huang, Y. [1 ]
Chen, T. [1 ,2 ]
Hu, Y. [1 ,2 ]
Li, Z. [1 ]
机构
[1] Shantou Univ, Shenzhen Childrens Hosp, Dept Radiol, Med Coll, Shenzhen, Peoples R China
[2] China Med Univ, Shenzhen Childrens Hosp, Dept Radiol, Shenzhen, Peoples R China
关键词
SKELETAL-MUSCLE; QUANTITATIVE MRI; RELAXATION-TIME; MEDIAN NERVE; DYSTROPHY; NUSINERSEN; PATTERN; BRAIN; BOYS;
D O I
10.1016/j.crad.2024.06.0040009-9260
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Spinal muscular atrophy (SMA) is an autosomal recessive genetic disease caused by the degeneration of the a-motor neurons in the anterior horn of the spinal cord. SMA is clinically characterized by progressive and symmetrical muscle weakness and muscle atrophy and ends up with systemic multisystem abnormalities. Quantitative MRI (qMRI) has the advantages of non-invasiveness, objective sensitivity, and high reproducibility, and has important clinical value in evaluating the severity of neuromuscular diseases and monitoring the efficacy of treatment. This article summarizes the clinical use of muscular MRI and magnetic resonance neurography in assessing the progress of SMA. (c) 2024 The Royal College of Radiologists. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
引用
收藏
页码:673 / 680
页数:8
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