Epidemic transmission modeling with fractional derivatives and environmental pathogens

被引:0
|
作者
Khalighi, Moein [1 ]
Ndairou, Faical [2 ]
Lahti, Leo [1 ]
机构
[1] Univ Turku, Fac Technol, Dept Comp, FI-20014 Yliopistonmaki, Finland
[2] Bulgarian Acad Sci, Inst Math & Informat, ul Akad G Bonchev,bl 8, Sofia 1113, Bulgaria
基金
芬兰科学院;
关键词
Mathematical modeling of COVID-19 pandemics; pathogens; environmental effect; fractional differential equations; numerical simulations; HIV-1 INFECTION MODEL; DYNAMICS; THRESHOLD; VIRUS;
D O I
10.1142/S1793524524500852
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
This research presents an advanced fractional-order compartmental model designed to delve into the complexities of COVID-19 transmission dynamics, specifically accounting for the influence of environmental pathogens on disease spread. By enhancing the classical compartmental framework, our model distinctively incorporates the effects of order derivatives and environmental shedding mechanisms on the basic reproduction numbers, thus offering a holistic perspective on transmission dynamics. Leveraging fractional calculus, the model adeptly captures the memory effect associated with disease spread, providing an authentic depiction of the virus's real-world propagation patterns. A thorough mathematical analysis confirming the existence, uniqueness and stability of the model's solutions emphasizes its robustness. Furthermore, the numerical simulations, meticulously calibrated with real COVID-19 case data, affirm the model's capacity to emulate observed transmission trends, demonstrating the pivotal role of environmental transmission vectors in shaping public health strategies. The study highlights the critical role of environmental sanitation and targeted interventions in controlling the pandemic's spread, suggesting new insights for research and policy-making in infectious disease management.
引用
收藏
页数:28
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