A case report of interstitial pneumonia induced by vedolizumab in a patient with ulcerative colitis

被引：0

作者：

Liu, Ailing ^{[1
]}

Ye, Susu ^{[2
]}

Diao, Zeyuan ^{[1
]}

Liu, Hua ^{[1
]}

Xu, Yonghong ^{[1
]}

Wu, Jun ^{[1
]}

Mao, Tao ^{[1
]}

Tian, Zibin ^{[1
]}

Ding, Xueli ^{[1
]}

机构：

[1] Qingdao Univ, Dept Gastroenterol, Affiliated Hosp, 16 Jiangsu Rd, Qingdao 266003, Shandong Provin, Peoples R China

[2] Qingdao Univ, Liver Dis Ctr, Affiliated Hosp, Qingdao, Peoples R China

来源：

MEDICINE | 2024年 / 103卷 / 31期

关键词：

interstitial pneumonia; ulcerative colitis; vedolizumab;

D O I：

10.1097/MD.0000000000039195

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Rationale:The interstitial pneumonia (IP) linked to vedolizumab (VDZ) in patients with ulcerative colitis (UC) is rare. Prompt diagnosis and treatment can improve patient outcomes.Patient concerns:A 39-year-old man with UC who received VDZ as sole therapy developed symptoms such as chest tightness, cough, and suffocation.Diagnoses:IP was confirmed through pulmonary function tests, chest computed tomography, and bronchoscopic biopsy.Interventions:The patient was given methylprednisolone and VDZ cessation.Outcomes:The patient's symptoms improved and remained symptom-free after nearly 2 years.Lessons:VDZ-induced IP should be considered when evaluating pulmonary infections in UC patients treated with VDZ.

引用

页数：2

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