Mitochondrial tonic for adoptive T cell therapies

被引:0
|
作者
Minton, Kirsty
机构
[1] Nature Reviews Immunology,
关键词
D O I
10.1038/s41577-024-01095-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A study in Cell describes a platform to supply exogenous mitochondria to CD8+ T cells via nanotubes, which boosts their antitumour efficacy.
引用
收藏
页码:777 / 777
页数:1
相关论文
共 50 条
  • [31] Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8+ T cell adoptive therapies in pre-clinical studies
    Wu, Meng-Han
    Valenca-Pereira, Felipe
    Cendali, Francesca
    Giddings, Emily L.
    Pham-Danis, Catherine
    Yarnell, Michael C.
    Novak, Amanda J.
    Brunetti, Tonya M.
    Thompson, Scott B.
    Henao-Mejia, Jorge
    Flavell, Richard A.
    D'Alessandro, Angelo
    Kohler, M. Eric
    Rincon, Mercedes
    NATURE COMMUNICATIONS, 2024, 15 (01)
  • [32] T-cell-based Immunotherapies for Haematological Cancers, Part B: A SWOT Analysis of Adoptive Cell Therapies
    Rallis, Kathrine S.
    Hillyar, Christopher R. T.
    Sideris, Michail
    Davies, Jeff K.
    ANTICANCER RESEARCH, 2021, 41 (03) : 1143 - 1156
  • [33] Neoantigen-Specific Adoptive Cell Therapies for Cancer: Making T-Cell Products More Personal
    Bianchi, Valentina
    Harari, Alexandre
    Coukos, George
    FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [34] Clinical Pharmacology Perspectives for Adoptive Cell Therapies in Oncology
    Huang, Weize
    Li, Junyi
    Liao, Michael Z.
    Liu, Stephanie N.
    Yu, Jiajie
    Jing, Jing
    Kotani, Naoki
    Kamen, Lynn
    Guelman, Sebastian
    Miles, Dale R.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2022, 112 (05) : 968 - 981
  • [35] Leveraging academic partnerships to advance adoptive cell therapies
    Adams, J. B.
    CYTOTHERAPY, 2020, 22 (05) : S139 - S139
  • [36] Enhancing adoptive cell therapies through exogenous regulation
    Richardson, Celeste
    Elpek, Kutlu
    Ols, Michelle
    Kassum, Tariq
    Shamah, Steve
    CANCER RESEARCH, 2018, 78 (13)
  • [37] PRECLINICAL MOUSE MODELS IN ADOPTIVE CELL THERAPIES OF CANCER
    Rajcevic, Uros
    Smole, Ante
    SLOVENIAN VETERINARY RESEARCH, 2022, 59 (04) : 173 - 184
  • [38] Group O plasma as a media supplement for CAR-T cells and other adoptive T-cell therapies
    Nelson, Randin C.
    Fellowes, Vicki
    Jin, Ping
    Liu, Hui
    Highfill, Steven L.
    Ren, Jiaqiang
    Szymanski, James
    Flegel, Willy A.
    Stroncek, David F.
    TRANSFUSION, 2020, 60 (05) : 1004 - 1014
  • [39] GENETIC MODIFICATION OF CD8+T CELLS TO EXPRESS EGFR: POTENTIAL APPLICATION FOR ADOPTIVE T CELL THERAPIES
    Casares, N.
    Lasarte, J. J.
    Lozano, T.
    Chocarro, S.
    del Valle, C.
    Gorraiz, M.
    Hervas-Stubbs, S.
    Sarobe, P.
    HUMAN GENE THERAPY, 2019, 30 (12) : A18 - A18
  • [40] Genetic Modification of CD8+ T Cells to Express EGFR: Potential Application for Adoptive T Cell Therapies
    Lozano, Teresa
    Chocarro, Silvia
    Martin, Celia
    Lasarte-Cia, Aritz
    del Valle, Cynthia
    Gorraiz, Marta
    Sarrion, Patricia
    de Galarreta, Marina Ruiz
    Lujambio, Amaia
    Hervas-Stubbs, Sandra
    Sarobe, Pablo
    Casares, Noelia
    Lasarte, Juan J.
    FRONTIERS IN IMMUNOLOGY, 2019, 10