Synthesis Morphological and Antimicrobial Characterization of Hydroxyapatite Nanoparticles for Biomedical Applications

被引:0
|
作者
Hossain, Nayem [1 ]
Chowdhury, M. Shakil [1 ]
Sarker, M. Abdul Hannan [1 ]
Huda, M. Nazmul [1 ]
Hamam, M. Rajib [2 ]
Islam, Safiul [1 ]
Mim, Juhi Jannat [1 ]
Chowdhury, Mohammad Asaduzzaman [3 ]
机构
[1] Int Univ Business Agr & Technol, Dept Mech Engn, IUBAT, Dhaka 1230, Bangladesh
[2] Dhaka Univ Engn & Technol, Dept Mat & Met Engn, Gazipur 1707, Bangladesh
[3] Dhaka Univ Engn & Technol Gazipur, Dept Mech Engn, Gazipur 1707, Bangladesh
来源
关键词
Hydroxyapatite; nanoparticle; biomedical application; morphology; antimicrobial performance; SILVER NANOPARTICLES; GOLD NANOPARTICLES; BONE; NANOCOMPOSITE; COMPOSITE; SCAFFOLDS; SILICON; SURFACE; APATITE; GLASS;
D O I
10.1142/S1793292024500954
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Nanoparticles (NPs) are promising candidates for different biomedical applications due to their excellent antimicrobial applications. However, the applications become limited due to the higher cost of NP synthesis. In his research work, Hydroxyapatite Nanoparticles (HANPs) have been synthesized in a cost-effective method to apply in biomedical applications. The synthesized HANPs have been characterized by different morphological and antimicrobial characterization methods. Ultraviolet-Visible (UV) spectroscopy was performed and a peak was obtained at 271nm which confirmed the formation of NPs and opened a new door for further analysis. Fourier Transformed Infrared Spectroscopy (FTIR) has been performed and the presence of functional groups such as hydroxides carbonates and phosphates have been identified. Transmission Electron Microscopy (TEM) analysis reveals the circular and smaller shape of the synthesized HANPs. The chemical elements of HA have been identified by EDS analysis. Sharp peaks identified by the X-Ray Diffraction (XRD) analysis confirm the formation of crystals in the synthesized HANPs. An excellent antimicrobial performance which is 99.99% has been obtained from the gram-positive and gram-negative bacterial strains. The obtained results suggest the potentiality of the synthesized HANPs in biomedical applications.
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页数:9
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