ONE POT SYNTHESIS OF ISOXAZOLONE DERIVATIVES USING IONIC LIQUID AS AN EFFICIENT CATALYST VIA MULTICOMPONENT REACTION

被引：0

作者：

Mokal, Ramesh A. ^{[1
]}

Jadhavar, Suresh C. ^{[1
]}

机构：

[1] Dr Babasaheb Ambedkar Marathwada Univ, Dept Chem, Yogeshwari Mahavidyalaya, Aurangabad, MH, India

来源：

HETEROCYCLIC LETTERS | 2024年 / 14卷 / 03期

关键词：

: Aryl aldehyde; ethyl acetoacetate; ionic liquid; BMIM][PF6; 6; isoxazolone; multicomponent reaction; etc; 3-COMPONENT SYNTHESIS; GREEN SYNTHESIS; ISOXAZOLE-5(4H)-ONES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and convenient route for the synthesis of isoxazol-5(4H)-one H )-one derivatives is described via multi-component condensation of aryl aldehyde, ethyl acetoacetate and hydroxyl amine under the influence of 1-butyl-3-methyl-imidazolium hexafluoro phosphate [BMIM][PF6] 6 ] ionic liquid as an efficient, cheaper and eco-friendly catalyst under conventional reflux condition in ethanol. The present protocol has several beneficial things such as simple work-up process, a cleaner reaction, optimum reaction time and good to excellent yields.

引用

页码：545 / 551

页数：7

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