Scattering effect for relative blood volume monitoring during hemodialysis

被引：0
|
作者：
Zhou, Lianqiao [1 ,2 ]
Li, Qinlan [1 ,2 ]
Wei, Shuang [5 ]
Wang, Shugang [5 ]
Cui, Jingqiang [5 ]
Wang, Guosheng [5 ]
Liu, Chong [2 ,4 ]
Su, Yewang [1 ,2 ,3 ]
机构：
[1] Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100190, Peoples R China
[2] Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China
[3] Chinese Acad Sci, Inst Mech, Beijing Key Lab Engn Construct & Mechanobiol, Beijing 100190, Peoples R China
[4] Chinese Acad Sci, State Key Lab High Temp Gas Dynam, Inst Mech, Beijing 100190, Peoples R China
[5] Tuoren Hlth Technol Ind Pk, Tuoren Med Device Res & Dev Inst Co Ltd, Henan Key Lab Med Polymer Mat Technol & Applicat, Changyuan Cty 453000, Henan, Peoples R China
来源：
SENSORS AND ACTUATORS A-PHYSICAL | 2024年 / 377卷
基金：
中国国家自然科学基金;
关键词：
Hemodialysis; Relative blood volume; Optical principle; Scattering; INTRADIALYTIC HYPOTENSION; DIALYSIS HYPOTENSION; LIGHT-SCATTERING; FUTURE;
D O I：
10.1016/j.sna.2024.115736
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
The long-term survival rate of hemodialysis patients is limited by hemodialysis-related complications, which are attributed to the inappropriate level of relative blood volume (RBV) after treatment. For the conventional optical monitoring methods, the RBV is usually overestimated, especially when the RBV varies in a wide range. Here, we find that the scattering effect of blood on incident light is the dominant factor of nonlinear measurement errors according to the numerical simulation results. Then a computational model considering both the absorption and scattering effect of blood is proposed and applied to a relative blood volume monitoring system (RBVMS). Finally, the RBVMS is validated in a commercial hemodialysis machine, showing a relatively low measurement error of 6.9 %. This result indicates the potential of the system for RBV monitoring during hemodialysis.
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页数：9
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