Identification of Immune-Related Gene Pair Signature to Predict Prognosis of Diffuse Large B-Cell Lymphoma Based on Bioinformatics Analyses

被引:0
|
作者
Davoodi-Moghaddam, Zeinab [1 ]
Jafari-Raddani, Farideh [1 ]
Bashash, Davood [1 ]
机构
[1] Shahid Beheshti Univ Med Sci, Sch Allied Med Sci, Dept Hematol & Blood Banking, Tehran, Iran
关键词
diffuse large B-cell lymphoma; immune-related signature; IRGPs; tumor immune microenvironment; bioinformatics; TUMOR-INFILTRATING LYMPHOCYTES; T-LYMPHOCYTES; FAVORABLE PROGNOSIS; OPEN-LABEL; R-IPI; EXPRESSION; COMPLEMENT; RITUXIMAB; CHEMOTHERAPY; MACROPHAGE;
D O I
10.1080/07357907.2024.2405184
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Since over one-third of DLBCL patients experience relapse or refractory after standard therapy, high-risk patients must be predicted. We developed a prognostic immune-related gene pairs (IRGPs) signature for DLBCL patients using bioinformatics analyses. This signature can predict the prognosis of these patients adequately, either alone or in combination with other clinical parameters. It hopes to improve the stratification and management of these patients for broad clinical applications.
引用
收藏
页码:858 / 875
页数:18
相关论文
共 50 条
  • [31] Identification and Validation of a DNA Damage Repair-Related Signature for Diffuse Large B-Cell Lymphoma
    Li, Yang
    Liu, Xiyang
    Chang, Yu
    Fan, Bingjie
    Shangguan, Chenxing
    Chen, Huan
    Zhang, Lei
    BIOMED RESEARCH INTERNATIONAL, 2022, 2022
  • [32] A 6-lncRNA signature predicts prognosis of diffuse large B-cell lymphoma
    Gao, Hongyu
    Wu, Bin
    Jin, Hong
    Yang, Wei
    JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2021, 35 (06) : 1 - 12
  • [33] Identification of novel gene signature to classify malignancy of diffuse large B-cell lymphoma in various animals
    Tanabe, Atsushi
    Ndzinu, Jerry
    Sahara, Hiroeki
    CANCER SCIENCE, 2025, 116 : 1031 - 1031
  • [34] Development of a Reproducible Prognostic Gene Signature to Predict the Clinical Outcome in Patients with Diffuse Large B-Cell Lymphoma
    Zamani-Ahmadmahmudi, Mohamad
    Nassiri, Seyed Mahdi
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [35] Development of a Reproducible Prognostic Gene Signature to Predict the Clinical Outcome in Patients with Diffuse Large B-Cell Lymphoma
    Mohamad Zamani-Ahmadmahmudi
    Seyed Mahdi Nassiri
    Scientific Reports, 9
  • [36] Identification of potential drugs for diffuse large b-cell lymphoma based on bioinformatics and Connectivity Map database
    Luo, Bin
    Gu, Yong-yao
    Wang, Xiao-dong
    Chen, Gang
    Peng, Zhi-gang
    PATHOLOGY RESEARCH AND PRACTICE, 2018, 214 (11) : 1854 - 1867
  • [37] HLA specificities are related to development and prognosis of diffuse large B-cell lymphoma
    Alcoceba, Miguel
    Sebastian, Elena
    Marin, Luis
    Balanzategui, Ana
    Eugenia Sarasquete, M.
    Carmen Chillon, M.
    Jimenez, Cristina
    Puig, Noemi
    Corral, Rocio
    Pardal, Emilia
    Grande, Carlos
    Luis Bello, Jose
    Albo, Carmen
    de la Cruz, Fatima
    Panizo, Carlos
    Martin, Alejandro
    Gonzalez-Barca, Eva
    Dolores Caballero, M.
    San Miguel, Jesus F.
    Garcia-Sanz, Ramon
    Gonzalez, Marcos
    BLOOD, 2013, 122 (08) : 1448 - 1454
  • [38] HLA SPECIFICITIES ARE CLOSELY RELATED TO PROGNOSIS OF DIFFUSE LARGE B-CELL LYMPHOMA
    Alcoceba, Miguel
    Sebastian, Elena
    Marin, Luis
    Balanzategui, Ana
    Sarasquete, Eugenia
    Chillon, Carmen
    Jimenez, Cristina
    Conde, Isabel
    Puig, Noemi
    Corral, Rocio
    Pardal, Emilia
    Grande, Carlos
    Bello, Jose L.
    Albo, Carmen
    Martin, Alejandro
    Gonzalez-Barca, Eva
    Caballero, Dolores
    San Miguel, Jesus F.
    Garcia-Sanz, Ramun
    Gonzalez, Marcos
    TISSUE ANTIGENS, 2013, 81 (05): : 284 - 284
  • [39] Immune signature and pathways investigation of adrenal gland diffuse large B-cell lymphoma
    Jia, Weijing
    Qi, Ruochen
    Zhang, Xiaoyan
    Liu, Kepu
    Zhang, Longlong
    Fan, Xiaozheng
    Yang, Bo
    Wang, Guohui
    Han, Shichao
    Ma, Shuaijun
    SCIENTIFIC REPORTS, 2025, 15 (01):
  • [40] Cytoplasmic Lipid Droplets Predict Worse Prognosis in Diffuse Large B-Cell Lymphoma
    Wang, Shu-Hsien
    Chiang, Po-Min
    Su, Yung-Yeh
    Yu, Yu-Ting
    Chen, Ya-Ping
    Chen, Tsai-Yun
    Medeiros, L. Jeffrey
    Chu, Chang-Yao
    Chen, Peng-Chieh
    Chang, Kung-Chao
    AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2024, 48 (11) : 1425 - 1438