Identification of Immune-Related Gene Pair Signature to Predict Prognosis of Diffuse Large B-Cell Lymphoma Based on Bioinformatics Analyses

被引：0

作者：

Davoodi-Moghaddam, Zeinab ^{[1
]}

Jafari-Raddani, Farideh ^{[1
]}

Bashash, Davood ^{[1
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Sch Allied Med Sci, Dept Hematol & Blood Banking, Tehran, Iran

来源：

CANCER INVESTIGATION | 2024年 / 42卷 / 10期

关键词：

diffuse large B-cell lymphoma; immune-related signature; IRGPs; tumor immune microenvironment; bioinformatics; TUMOR-INFILTRATING LYMPHOCYTES; T-LYMPHOCYTES; FAVORABLE PROGNOSIS; OPEN-LABEL; R-IPI; EXPRESSION; COMPLEMENT; RITUXIMAB; CHEMOTHERAPY; MACROPHAGE;

D O I：

10.1080/07357907.2024.2405184

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Since over one-third of DLBCL patients experience relapse or refractory after standard therapy, high-risk patients must be predicted. We developed a prognostic immune-related gene pairs (IRGPs) signature for DLBCL patients using bioinformatics analyses. This signature can predict the prognosis of these patients adequately, either alone or in combination with other clinical parameters. It hopes to improve the stratification and management of these patients for broad clinical applications.

引用

页码：858 / 875

页数：18

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