Vaccinations for emerging and re-emerging viral diseases

被引:0
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作者
Weichel, Hanna-Marie [1 ,2 ,3 ,4 ]
Koch, Till [4 ,5 ]
机构
[1] Univ Klinikum Hamburg Eppendorf, Inst Infektionsforschung & Impfstoffentwicklung II, Zent Innere Med, Hamburg, Germany
[2] Bernhard Nocht Inst Tropenmed, Abt Klin Immunol Infektionskrankheiten, Hamburg, Germany
[3] Univ Klinikum Hamburg Eppendorf, Ambulanzzentrum Infektiol, Hamburg, Germany
[4] Deutsch Zentrum Infektionsforschung DZIF, Standort Hamburg Lubeck Borstel Riems, Hamburg, Germany
[5] Univ Klinikum Hamburg Eppendorf, Antibiot Stewardship Team, Hamburg, Germany
来源
关键词
Viral zoonoses; Filoviridae; Influenza vaccines; Highly pathogenic coronaviruses; Arbovirus infections; TETRAVALENT DENGUE VACCINE; DOUBLE-BLIND; INFLUENZA; EFFICACY; SAFETY; PHASE-3;
D O I
10.1007/s00108-024-01780-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Emerging or re-emerging viral diseases have a pandemic potential and threaten global health. Vaccination is of crucial importance in the prevention of emerging and re-emerging viral diseases. Objective: Description of the current status of vaccine development against Filoviridae, highly pathogenic coronaviruses, smallpox viruses, influenza viruses and arboviruses. Material and methods: Focused literature search. Results: The World Health Organization (WHO) regularly publishes a list of infectious diseases that are expected to pose a major threat to humanity as they are could potentially trigger new pandemics; however, in addition to these human-to-human transmissible diseases, some arboviruses also have pandemic potential. In recent years numerous new vaccines, some of which are highly effective, have been licensed against new and re-emerging viral diseases and other promising vaccine candidates are currently in development. Conclusion: There are still gaps in the development of vaccines in the area of Filoviridae and highly pathogenic coronaviruses. Vaccinations against smallpox viruses have been available for a long time. Developing influenza vaccines against novel strains in a timely manner is a challenge and universal influenza vaccines could be a possible solution. Modern vaccines are available against the arboviruses dengue and Chikungunya fever.
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页数:10
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