Bio-properties of Mg-RE alloys: an applied study on cytotoxicity and genotoxicity

被引：0
|
作者：
Djebari, Kenza [1 ]
Turen, Yunus [1 ]
Elen, Levent [1 ]
Ahlatci, Hayrettin [1 ]
Bozer, Busra Moran [2 ]
Cicek, Bunyamin [3 ]
机构：
[1] Karabuk Univ, Fac Engn, Dept Met & Mat Engn, Karabuk, Turkiye
[2] Hitit Univ, Sci Tech Applicat & Res Ctr, Corum, Turkiye
[3] Hitit Univ, Tech Sci Vocat Coll, Corum, Turkiye
来源：
CANADIAN METALLURGICAL QUARTERLY | 2024年
关键词：
Mg-RE alloys; rare elements; biocompatibility; cytotoxicity; genotoxicity; BIODEGRADABLE MAGNESIUM ALLOYS; ZN-Y ALLOYS; MECHANICAL-PROPERTIES; CORROSION-RESISTANCE; RARE-EARTH; IN-VITRO; PROFILE ANALYSIS; MICROSTRUCTURE; GD; BIOCOMPATIBILITY;
D O I：
10.1080/00084433.2024.2397190
中图分类号：
TF [冶金工业];
学科分类号：
0806 ;
摘要：
This study presents a comprehensive review of magnesium alloys with rare elements. It discusses Mg-RE alloys and includes an experimental process. Thus, the data obtained by examining Mg-RE alloys provided a better interpretation of the experimental study. In this study's investigation report, Mg-RE alloys were thoroughly analyzed. In the experimental part, the cytotoxic and genotoxic results of the rare elements added to the Mg-Zn-RE master alloy are discussed. Experiments were carried out by adding Nd and Ce to this master alloy in inverse proportions. In cytotoxic data, it was observed that the viability rate in bacteria increased by up to 200%. In addition, significant genotoxic results of Mg-RE alloys were obtained, which are uncommon in the literature. As a result, a new perspective on Mg-RE alloys has been created. Cette & eacute;tude pr & eacute;sente un examen complet des alliages de magn & eacute;sium contenant des & eacute;l & eacute;ments rares. Elle discute des alliages Mg-ER et comprend un proc & eacute;d & eacute; exp & eacute;rimental. Ainsi, les donn & eacute;es obtenues en examinant les alliages Mg-ER ont fourni une meilleure interpr & eacute;tation de l'& eacute;tude exp & eacute;rimentale. Dans le rapport d'investigation de cette & eacute;tude, on a analys & eacute; & agrave; fond les alliages Mg-ER. Dans la partie exp & eacute;rimentale, on discute des r & eacute;sultats cytotoxiques et g & eacute;notoxiques des & eacute;l & eacute;ments rares ajout & eacute;s & agrave; l'alliage m & egrave;re Mg-Zn-ER. On a r & eacute;alis & eacute; des exp & eacute;riences en ajoutant du Nd et du Ce & agrave; cet alliage m & egrave;re en proportions inverses. Dans les donn & eacute;es cytotoxiques, on a observ & eacute; que le taux de viabilit & eacute; des bact & eacute;ries a augment & eacute; jusqu'& agrave; 200%. De plus, on a obtenu des r & eacute;sultats g & eacute;notoxiques significatifs des alliages Mg-ER, qui sont peu communs dans la litt & eacute;rature. Par cons & eacute;quent, on a cr & eacute;& eacute; une nouvelle perspective sur les alliages Mg-ER.
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页数：13
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