Endoscopic duodenal mucosa ablation: the future of diabetes treatment?

被引：0
|
作者：
Musso, Giovanni [1 ]
Cassader, Maurizio [2 ]
Gambino, Roberto [2 ]
机构：
[1] Univ Turin, San Luigi Gonzaga Hosp, MECAU, Turin, Italy
[2] Univ Turin, Dept Med Sci, Citta Salute & Sci, Turin, Italy
来源：
TRENDS IN MOLECULAR MEDICINE | 2024年 / 30卷 / 07期
关键词：
ELECTROPORATION THERAPY; INSULIN;
D O I：
10.1016/j.molmed.2024.03.003
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Duodenal mucosa ablation (DMA) is a novel approach to treat diabetes, consisting of endoscopic ablation of dysfunctional diabetic duodenal mucosa, which, following the healing response, is replaced by normally functioning mucosa. Two techniques, duodenal mucosal resurfacing (DMR) and recellularization via electroporation therapy (ReCET), recently showed promise in type 2 diabetes mellitus (T2DM) patients.
引用
收藏
页码：612 / 616
页数：5
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