Effect of Selenium and Selenoproteins on Radiation Resistance

被引:1
|
作者
Zhang, Shidi [1 ]
Zhang, Guowei [1 ,2 ]
Wang, Pengjie [1 ]
Wang, Lianshun [3 ]
Fang, Bing [1 ]
Huang, Jiaqiang [1 ]
机构
[1] China Agr Univ, Beijing Adv Innovat Ctr Food Nutr & Human Hlth, Dept Nutr & Hlth, Beijing 100083, Peoples R China
[2] LLC Co Hongda Salt Ind, Tacheng 834700, Hoboksar Mongol, Peoples R China
[3] Dalian Ocean Univ, Coll Fisheries & Life Sci, Dalian 116023, Peoples R China
基金
中国国家自然科学基金; 国家重点研发计划;
关键词
selenium; radiation resistance; mechanism; DNA-DAMAGE RESPONSE; GLUTATHIONE-PEROXIDASE; GENE-EXPRESSION; SUPEROXIDE DISMUTASE; OXIDATIVE STRESS; PROSTATE-CANCER; IMMUNE-SYSTEM; ANTIOXIDANT; CELL; SUPPLEMENTATION;
D O I
10.3390/nu16172902
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
With the advancement of radiological medicine and nuclear industry technology, radiation is increasingly used to diagnose human health disorders. However, large-scale nuclear leakage has heightened concerns about the impact on human organs and tissues. Selenium is an essential trace element that functions in the body mainly in the form of selenoproteins. Selenium and selenoproteins can protect against radiation by stimulating antioxidant actions, DNA repair functions, and immune enhancement. While studies on reducing radiation through antioxidants have been conducted for many years, the underlying mechanisms of selenium and selenoproteins as significant antioxidants in radiation damage mitigation remain incompletely understood. Therefore, this paper aims to provide new insights into developing safe and effective radiation protection agents by summarizing the anti-radiation mechanism of selenium and selenoproteins.
引用
收藏
页数:14
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