Terahertz nonstationary high-resolution spectroscopy: state-of-the-art and trends of development

被引：0
|
作者：
Vaks, Vladimir l. [1 ,2 ]
Domracheva, Elena G. [1 ,2 ]
Chernyaeva, Mariya B. [1 ,2 ]
Anfertev, Vladimir A. [1 ,2 ]
Yablokov, Anton A. [1 ,2 ]
机构：
[1] Russian Acad Sci, Inst Phys Microstruct, Nizhnii Novgorod, Russia
[2] Lobachevsky State Univ Nizhny Novgorod, Nizhnii Novgorod, Russia
来源：
JOURNAL OF OPTICAL TECHNOLOGY | 2024年 / 91卷 / 01期
基金：
俄罗斯科学基金会;
关键词：
Tissue;
D O I：
10.1364/JOT.91.000023
中图分类号：
O43 [光学];
学科分类号：
070207 ; 0803 ;
摘要：
Subject of study. The subject of this study was the chemical composition of multicomponent gas mixtures of biological origin. Aim of study. . This study aimed to construct the metabolic profiles of diseases by studying biological samples (tissues of ear-nose-throat organs, urine) with high-resolution terahertz (THz) spectroscopy. Method. Spectroscopy based on nonstationary effects, such as inducing and decaying the free dumping polarization in a gas sample during the interaction of radiation and gas molecules, is a highly sensitive method for investigating multi- component gas mixtures. A spectrometer based on these principles operates in the modes with the phase switching or fast sweeping of the probing radiation. Main results. Some experimental results of using high-resolution THz spectroscopy for medical diagnostics and treatment control are presented in this paper. The multicomponent gas mixtures, such as vapors or thermal decomposition products of various samples [biological liquids (urine) and pathological tissues of living organisms], were studied using THz nonstationary spectrometers for developing diagnostic methods. The results of experimental data analysis reveal the markers for specified diseases of living organisms (diabetes, pathology tissues of ear-nose-throat organs) or substances appearing during therapeutic treatment (nephrotoxical influence of chemotherapy). Practical significance. THz nonstationary high-resolution spectroscopy can be considered a prospective analytical method of spectral analysis for fundamental and applied research. (c) 2024 Optica Publishing Group
引用
收藏
页码：23 / 28
页数：6
相关论文
共 50 条
  • [1] STATE-OF-THE-ART ON HIGH-RESOLUTION CARS
    SCHROTTER, HW
    BOQUILLON, JP
    [J]. VIBRATIONAL SPECTRA AND STRUCTURE, VOL 17 B: RAMAN SPECTROSCOPY SIXTY YEARS ON, 1989, 17 : 1 - 14
  • [2] State-of-the-art of small animal imaging with high-resolution SPECT
    Nikolaus, S
    Wirrwar, A
    Antke, C
    Kley, K
    Müller, HW
    [J]. NUKLEARMEDIZIN-NUCLEAR MEDICINE, 2005, 44 (06): : 257 - 266
  • [3] High-resolution high-count-rate X-ray spectroscopy with state-of-the-art silicon detectors
    Struder, L
    Fiorini, C
    Gatti, E
    Hartmann, R
    Holl, P
    Krause, N
    Lechner, P
    Longoni, A
    Lutz, G
    Kemmer, J
    Meidinger, N
    Popp, M
    Soltau, H
    Weber, U
    von Zanthier, C
    [J]. JOURNAL OF SYNCHROTRON RADIATION, 1998, 5 : 268 - 274
  • [4] Statistical dynamic image reconstruction in state-of-the-art high-resolution PET
    Rahmim, A
    Cheng, JC
    Blinder, S
    Camborde, ML
    Sossi, V
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2005, 50 (20): : 4887 - 4912
  • [5] High-resolution imaging spectroscopy at terahertz frequencies
    Brown, Robert L.
    Kerr, Anthony R.
    Thompson, A. Richard
    Schwab, Frederic R.
    [J]. Proceedings of the Colloquium of the International Astronomical Union, 1600,
  • [6] LASER SPECTROSCOPY OF MOLECULES - STATE-OF-THE-ART AND POSSIBLE TRENDS
    DEMTRODER, W
    [J]. FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 1990, 337 (07): : 830 - 834
  • [7] Satellite paging: State-of-the-art and development trends
    Soloviev, A
    Smirnov, S
    [J]. 3RD INTERNATIONAL CONFERENCE ON SATELLITE COMMUNICATIONS - PROCEEDINGS OF ICSC'98, VOL I, 1998, : 189 - 191
  • [8] Galvanomagnetic sensors: The state-of-the-art and development trends
    Rozenblat, MA
    [J]. AUTOMATION AND REMOTE CONTROL, 1997, 58 (01) : 1 - 34
  • [9] State-of-the-Art and Development Trends of AUV Intelligence
    Huang Y.
    Li Y.
    Yu J.
    Li S.
    Feng X.
    [J]. Jiqiren/Robot, 2020, 42 (02): : 215 - 231
  • [10] Performance Evaluation of State-of-the-Art High-Resolution Time-of-Flight Cameras
    Paredes, Alvaro Lopez
    Song, Qiang
    Heredia Conde, Miguel
    [J]. IEEE SENSORS JOURNAL, 2023, 23 (12) : 13711 - 13727
12345