EFFECTS OF VACCINATION AND SATURATED TREATMENT ON COVID-19 TRANSMISSION IN INDIA: DETERMINISTIC AND STOCHASTIC APPROACHES

被引:1
|
作者
Saha, Pritam [1 ]
Pal, Kalyan Kumar [2 ]
Ghosh, Uttam [1 ]
Tiwari, Pankaj Kumar [2 ]
机构
[1] Univ Calcutta, Dept Appl Math, Kolkata 700009, India
[2] Indian Inst Informat Technol, Dept Basic Sci & Humanities, Bhagalpur 813210, India
关键词
COVID-19; Parameter estimation; Backward bifurcation; Sensitivity analysis; Stationary distribution; SENSITIVITY-ANALYSIS; MODEL; UNCERTAINTY; DYNAMICS; OUTBREAK;
D O I
10.1142/S021833902450044X
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
This study explores an epidemic model elucidating the dynamics of COVID-19 transmission amidst vaccination and saturated treatment interventions. The investigation encompasses both deterministic and stochastic frameworks, considering constant and fluctuating environments, utilizing COVID-19 data from India for empirical validation. Through rigorous mathematical and numerical analyses, we ascertain pivotal insights. Our deterministic model unveils a critical phenomenon: the occurrence of backward bifurcation at R-0 = 1, underscoring that merely reducing the basic reproduction number below unity does not ensure disease eradication. Sensitivity analyses underscore the acceleration of epidemic spread with higher transmission rates, yet mitigation measures such as vaccination and comprehensive treatment can effectively reduce the basic reproduction number below unity. Within the stochastic framework, we establish the existence of a unique global positive solution. We delineate conditions for disease extinction or persistence and identify criteria for the emergence of stationary distribution, reflecting the sustained presence of infection within the community. Our findings elucidate that while smaller noise intensities sustain disease prevalence, heightened noise levels lead to complete eradication of the infection.
引用
收藏
页码:53 / 99
页数:47
相关论文
共 50 条
  • [21] Stochastic near-optimal controls for treatment and vaccination in a COVID-19 model with transmission incorporating Lévy jumps
    Bouggar, Driss
    El Fatini, Mohamed
    Nasri, Bouchra
    Petersson, Roger
    Sekkak, Idriss
    STOCHASTICS-AN INTERNATIONAL JOURNAL OF PROBABILITY AND STOCHASTIC PROCESSES, 2024, 96 (01) : 887 - 920
  • [22] Deterministic and Stochastic Simulation of the COVID-19 Epidemic with the SEIR Model
    Balsa, Carlos
    Guarda, Teresa
    Lopes, Isabel
    Rufino, Jose
    PROCEEDINGS OF 2021 16TH IBERIAN CONFERENCE ON INFORMATION SYSTEMS AND TECHNOLOGIES (CISTI'2021), 2021,
  • [23] COVID-19: Pathophysiology, Transmission, and Drug Development for Therapeutic Treatment and Vaccination Strategies
    Singh, Vishal Kumar
    Chaurasia, Himani
    Mishra, Richa
    Srivastava, Ritika
    Yadav, Aditya K.
    Dwivedi, Jayati
    Singh, Prashant
    Singh, Ramendra K.
    CURRENT PHARMACEUTICAL DESIGN, 2022, 28 (27) : 2211 - 2233
  • [24] COVID-19 in the elderly people and advances in vaccination approaches
    Dhama, Kuldeep
    Patel, Shailesh Kumar
    Natesan, Senthilkumar
    Vora, Kranti Suresh
    Yatoo, Mohd Iqbal
    Tiwari, Ruchi
    Saxena, Shailendra K.
    Singh, Karam Pal
    Singh, Rajendra
    Malik, Yashpal Singh
    HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2020, 16 (12) : 2938 - 2943
  • [25] Nonlinear dynamic epidemiological analysis of effects of vaccination and dynamic transmission on COVID-19
    Kambali, Prashant N.
    Abbasi, Amirhassan
    Nataraj, C.
    NONLINEAR DYNAMICS, 2023, 111 (01) : 951 - 963
  • [26] EFFECTS OF VACCINATION ON THE TRANSMISSION DYNAMICS OF COVID-19 IN DOUGHERTY COUNTY OF GEORGIA, USA
    Pantha, Buddhi
    Mohammed-Awel, Jemal
    Vaidya, Naveen K.
    JOURNAL OF BIOLOGICAL SYSTEMS, 2022, 30 (03) : 553 - 583
  • [27] Nonlinear dynamic epidemiological analysis of effects of vaccination and dynamic transmission on COVID-19
    Prashant N. Kambali
    Amirhassan Abbasi
    C. Nataraj
    Nonlinear Dynamics, 2023, 111 : 951 - 963
  • [28] Inclusive Analysis of Covid-19 disease and Vaccination in India
    Thakkar, Dakshita
    Jha, Neha
    Agarwal, Diksha
    Anand, Saurabh
    Pradhan, Rahul
    2021 5th International Conference on Information Systems and Computer Networks, ISCON 2021, 2021,
  • [29] An assessment of the strategy and status of COVID-19 vaccination in India
    Sneh Lata Gupta
    Surbhi Goswami
    Ananya Anand
    Namrata Naman
    Priya Kumari
    Priyanka Sharma
    Rishi K. Jaiswal
    Immunologic Research, 2023, 71 : 565 - 577
  • [30] An assessment of the strategy and status of COVID-19 vaccination in India
    Gupta, Sneh Lata
    Goswami, Surbhi
    Anand, Ananya
    Naman, Namrata
    Kumari, Priya
    Sharma, Priyanka
    Jaiswal, Rishi K.
    IMMUNOLOGIC RESEARCH, 2023, 71 (04) : 565 - 577