Targeting serotonin signaling in the gut to limit colitis via 5-HT7 receptor antagonism

被引：0
|
作者：
Schumacher, Michael A. [1 ,2 ]
机构：
[1] Univ Southern Calif, Keck Sch Med, Dept Pediat, Los Angeles, CA 90007 USA
[2] Childrens Hosp Los Angeles, Saban Res Inst, Los Angeles, CA 90027 USA
来源：
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY | 2024年 / 327卷 / 03期
基金：
美国国家卫生研究院;
关键词：
colitis; 5HT7; IBD; serotonin; 5-HYDROXYTRYPTAMINE;
D O I：
10.1152/ajpgi.00181.2024
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
下载
收藏
页码：G454 / G455
页数：2
相关论文
共 50 条
  • [21] Serotonin (5-HT)1A receptor agonism and 5-HT7 receptor antagonism ameliorate the subchronic phencyclidine-induced deficit in executive functioning in mice
    Rajagopal, Lakshmi
    Massey, Bill W.
    Michael, Eric
    Meltzer, Herbert Y.
    PSYCHOPHARMACOLOGY, 2016, 233 (04) : 649 - 660
  • [22] Current Limitations and Candidate Potential of 5-HT7 Receptor Antagonism in Psychiatric Pharmacotherapy
    Okubo, Ruri
    Hasegawa, Toshiki
    Fukuyama, Kouji
    Shiroyama, Takashi
    Okada, Motohiro
    FRONTIERS IN PSYCHIATRY, 2021, 12
  • [23] Role of physiochemical properties on the residence time of serotonin 7 (5-HT7) receptor ligands
    Penna, E.
    Niso, M.
    Lacivita, E.
    Perrone-Capano, C.
    Crispino, M.
    Leopoldo, M.
    ACTA PHYSIOLOGICA, 2019, 227 : 94 - 94
  • [24] Human serotonin 5-HT7 receptor: cloning and pharmacological characterisation of two receptor variants
    Stam, NJ
    Roesink, C
    Dijcks, F
    Garritsen, A
    vanHerpen, A
    Olijve, W
    FEBS LETTERS, 1997, 413 (03) : 489 - 494
  • [25] Selective agonists for serotonin 7 (5-HT7) receptor and their applications in preclinical models: an overview
    Di Pilato, Pantaleo
    Niso, Mauro
    Adriani, Walter
    Romano, Emilia
    Travaglini, Domenica
    Berardi, Francesco
    Colabufo, Nicola A.
    Perrone, Roberto
    Laviola, Giovanni
    Lacivita, Enza
    Leopoldo, Marcello
    REVIEWS IN THE NEUROSCIENCES, 2014, 25 (03) : 401 - 415
  • [26] Amelioration of Tau pathology and memory deficits by targeting 5-HT7 receptor
    Labus, Josephine
    Roehrs, Kian-Fritz
    Ackmann, Jana
    Varbanov, Hristo
    Mueller, Franziska E.
    Jia, Shaobo
    Jahreis, Kathrin
    Vollbrecht, Anna-Lena
    Butzlaff, Malte
    Schill, Yvonne
    Guseva, Daria
    Boehm, Katrin
    Kaushik, Rahul
    Bijata, Monika
    Marin, Philippe
    Chaumont-Dubel, Severine
    Zeug, Andre
    Dityatev, Alexander
    Ponimaskin, Evgeni
    PROGRESS IN NEUROBIOLOGY, 2021, 197
  • [27] The Role of Serotonin 5-HT7 Receptor on Penicillin-Induced Epileptiform Activity
    Kocacan, Suleyman Emre
    Arslan, Gokhan
    Rzayev, Emil
    Agar, Erdal
    Ayyildiz, Mustafa
    ACTA PHYSIOLOGICA, 2022, 234 : 12 - 12
  • [28] Positive Association of the Serotonin 5-HT7 Receptor Gene with Schizophrenia in a Japanese Population
    Masashi Ikeda
    Nakao Iwata
    Tsuyoshi Kitajima
    Tatsuyo Suzuki
    Yoshio Yamanouchi
    Yoko Kinoshita
    Norio Ozaki
    Neuropsychopharmacology, 2006, 31 : 866 - 871
  • [29] Changes in 5-HT7 serotonin receptor mRNA expression with aging in rat brain
    Kohen, R
    Heidmann, DEA
    Anthony, J
    White, SS
    Hamblin, MW
    Szot, P
    MOLECULAR BRAIN RESEARCH, 2000, 79 (1-2): : 163 - 168
  • [30] Positive association of the serotonin 5-HT7 receptor gene with schizophrenia in a Japanese population
    Ikeda, M
    Iwata, N
    Kitajima, T
    Suzuki, T
    Yamanouchi, Y
    Kinoshita, Y
    Ozaki, N
    NEUROPSYCHOPHARMACOLOGY, 2006, 31 (04) : 866 - 871
12345