Could Vaccination against COVID-19 Trigger Immune-Mediated Inflammatory Diseases?

被引：0

作者：

Liakou, Aikaterini I. ^{[1
]}

Tsantes, Andreas G. ^{[2
,3
]}

Routsi, Eleni ^{[1
]}

Agiasofitou, Efthymia ^{[1
]}

Kalamata, Magdalini ^{[1
]}

Bompou, Evangelia-Konstantina ^{[1
]}

Tsante, Konstantina A. ^{[2
]}

Vladeni, Soultana ^{[1
]}

Chatzidimitriou, Eleni ^{[1
]}

Kotsafti, Ourania ^{[1
]}

Samonis, George ^{[4
,5
]}

Bonovas, Stefanos ^{[6
,7
]}

Stratigos, Alexander I. ^{[1
]}

机构：

[1] Natl & Kapodistrian Univ Athens, Andreas Sygros Hosp, Med Sch, Dept Dermatol Venereol 1, Athens 16121, Greece

[2] Natl & Kapodistrian Univ Athens, Attikon Hosp, Med Sch, Lab Haematol & Blood Bank Unit, Athens 12462, Greece

[3] St Savvas Oncol Hosp, Microbiol Dept, Athens 11522, Greece

[4] Univ Crete, Dept Med, Iraklion 71500, Greece

[5] Metropolitan Hosp, Dept Oncol, Athens 18547, Greece

[6] Humanitas Univ, Dept Biomed Sci, I-20072 Milan, Italy

[7] IRCCS, Humanitas Res Hosp, Milan, Italy

来源：

JOURNAL OF CLINICAL MEDICINE | 2024年 / 13卷 / 16期

关键词：

immune-mediated inflammatory diseases; COVID-19; vaccine; flare; onset; hidradenitis;

D O I：

10.3390/jcm13164617

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Exacerbations and new onset of immune-mediated inflammatory diseases, such as psoriasis and hidradenitis suppurativa, have been reported following COVID-19 vaccination. In patients with hidradenitis suppurativa, recent studies have shown that those who received mRNA vaccines were 3.5 times as likely to develop flares following vaccination compared to patients who received non-mRNA vaccines, indicating that mRNA COVID-19 vaccines are associated with hidradenitis suppurativa flares. Similar findings have been found in other studies evaluating the association between COVID-19 vaccines and other immune-mediated inflammatory diseases such as psoriasis, atopic dermatitis, lichen planus, and alopecia areata. However, further research is warranted in larger populations to validate these findings.

引用

页数：10

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