Letter to the editor on "The risk of clinically-relevant pancreatic fistula after pancreaticoduodenectomy is better predicted by a postoperative trend in drain fluid amylase compared to day 1 values in isolation"

staff doctor, senior doctor, or junior doctor completed the electronic medical record. As a rule, in order to maintain the quality of diagnosis, photographs of the surgical wound were taken for all patients, and when superficial or deep wound infection was suspected, culture tests were necessarily performed. tions pointed out by Jing et al and showed no difference between 2 groups in this study. Therefore, we did not discuss the postoperative complications. Nonclean wound, defined by the CDC wound classification, is a risk factor for 30-day readmission due to infectious complications including SSI.3 In a meta-analysis, Swaminathan et al4 reported the efficacy of PI for wound irrigation in laparotomy. However, of the 13 randomized controlled trials (RCTs) analyzed, 3 RCTs were for spinal surgery, 2 RCTs were regarding intraperitoneal lavage, and 1 was a comparison with the topical administration of rifampicin. Of the other 7 RCTs, 4 were reported after the establishment of the CDC guideline.2 Only 1 reported that wound irrigation with PI demonstrate the superiority of PI in preventing the occurrence of SSI, similar to our results. We believe that the results of metaanalyses should be interpreted with caution. needed for gastroenterological surgery.