The Role of Artificial Intelligence in Revolutionizing Pharmacological Research

被引:0
|
作者
Bhatia, Nitish [1 ]
Khan, Mohd Masih Uzzaman [2 ]
Arora, Saahil [3 ]
机构
[1] Vishwakarma Univ, Sch Pharm, Pune, Maharashtra, India
[2] Qassim Univ, Unaizah Coll Pharm, Dept Pharmaceut Chem & Pharmacognosy, Unaizah, Saudi Arabia
[3] G D Goenka Univ, Sch Hlth & Allied Sci, Gurugram, Haryana, India
关键词
Artificial Intelligence; Pharmacology; Drug Discovery; Drug Repurposing; Toxicity Prediction; Personalized Medicine;
D O I
10.1007/s40495-024-00367-x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Purpose of ReviewThe integration of Artificial Intelligence (AI) has ushered in a transformative era in pharmacological research, offering solutions to longstanding challenges associated with high costs and protracted timelines. The primary objective of this review is to provide a comprehensive overview of the current state of AI in pharmacological research, delineate its multifaceted applications, and underscore its consequential impact.Recent FindingsIn the realm of drug discovery, AI has emerged as a potent catalyst, leveraging machine learning to scrutinize vast datasets. This approach has facilitated the precise identification of potential drugs, significantly expediting the drug discovery process. Furthermore, AI has revolutionized virtual screening techniques, hastening the identification of promising drug candidates.The applications extend to personalized medicine, where AI plays a pivotal role in recommending tailored drug regimens based on individual genetics and medical history. Simultaneously, it aids in the stratification of patient subpopulations, ensuring optimized treatments.AI's influence is also evident in the realm of drug toxicity prediction, offering an invaluable tool for the early identification of safety concerns. The technology is set to impact pharmacological research by advancing our understanding of biological pathways, predicting long-term drug effects, enhancing regulatory compliance, and optimizing drug manufacturing processes.Recent FindingsIn the realm of drug discovery, AI has emerged as a potent catalyst, leveraging machine learning to scrutinize vast datasets. This approach has facilitated the precise identification of potential drugs, significantly expediting the drug discovery process. Furthermore, AI has revolutionized virtual screening techniques, hastening the identification of promising drug candidates.The applications extend to personalized medicine, where AI plays a pivotal role in recommending tailored drug regimens based on individual genetics and medical history. Simultaneously, it aids in the stratification of patient subpopulations, ensuring optimized treatments.AI's influence is also evident in the realm of drug toxicity prediction, offering an invaluable tool for the early identification of safety concerns. The technology is set to impact pharmacological research by advancing our understanding of biological pathways, predicting long-term drug effects, enhancing regulatory compliance, and optimizing drug manufacturing processes.Recent FindingsIn the realm of drug discovery, AI has emerged as a potent catalyst, leveraging machine learning to scrutinize vast datasets. This approach has facilitated the precise identification of potential drugs, significantly expediting the drug discovery process. Furthermore, AI has revolutionized virtual screening techniques, hastening the identification of promising drug candidates.The applications extend to personalized medicine, where AI plays a pivotal role in recommending tailored drug regimens based on individual genetics and medical history. Simultaneously, it aids in the stratification of patient subpopulations, ensuring optimized treatments.AI's influence is also evident in the realm of drug toxicity prediction, offering an invaluable tool for the early identification of safety concerns. The technology is set to impact pharmacological research by advancing our understanding of biological pathways, predicting long-term drug effects, enhancing regulatory compliance, and optimizing drug manufacturing processes. SummaryIn summary, AI's diverse and profound applications in pharmacological research, particularly in drug development, underscore its transformative potential. However, ethical and regulatory considerations are paramount. Proposed frameworks seek to ensure the responsible adoption of AI in healthcare, recognizing the need for a balanced approach that maximizes the benefits while safeguarding ethical principles. The continued responsible harnessing of AI in pharmacological research promises to reshape the landscape of healthcare and drug development.
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