BACKGROUND: Serial blood pressure and heart rate measurements, particularly obtained by the patients at home, are currently recommended for the management of patients. METHODS: Home blood pressure and heart rate measurements were obtained by an 81-year old husband and his 74-year old wife in the morning and evening, over the course of an entire month. RESULTS: Morning and evening systolic blood pressure (129.9 f 5.5, 125.9 f 10.2, respectively), and diastolic blood pressure (69.2 f 4.0, 70.1 f 5.3) were not different (P> P > .05), heart rate (61.2 f 2.9, 69.0 f 5.5) was higher in the evening (P P = .00001) in the husband, while systolic blood pressure (134.7 f 9.6, 119.0 f 12.0) and diastolic blood pressure (78.6 f 5.6, 72.1 f 7.3) were higher in the morning (P P = .00001, P = .00031), and heart rate (62.7 f 4.7, 68.2 f 4.6) was higher in the evening (P P = .00017) in the wife. CONCLUSIONS: Patient-generated serial home blood pressure and heart rate logs provide essential data for the patients' management and could potentially be useful in research; circadian variation of blood pressure and heart rate calls for implementation of chronotherapeutic principles for the time of drug administration. (c) 2024 Elsevier Inc. All rights reserved.