CRISPR-based screening pinpoints H2AZ1 as a driver of senescence in human mesenchymal stem cells

被引:3
|
作者
Li, Ming-Heng [1 ,3 ,6 ,7 ,8 ]
Jiang, Xiaoyu [2 ,3 ,6 ,7 ,8 ]
Jing, Yaobin [2 ,3 ,12 ]
Yan, Kaowen [2 ,3 ,6 ,7 ,8 ]
Bi, Shi-Jia [1 ,3 ,6 ,7 ,8 ]
Wang, Si [9 ,10 ,11 ,13 ]
Ma, Shuai [2 ,3 ,6 ,7 ,8 ,13 ]
Liu, Guang-Hui [2 ,3 ,6 ,7 ,8 ,9 ,10 ,11 ,12 ,13 ]
Zhang, Weiqi [4 ,5 ,6 ,7 ,13 ]
Sun, Shuhui [2 ,3 ,6 ,8 ,14 ]
Qu, Jing [1 ,2 ,3 ,6 ,7 ,8 ,13 ,14 ]
机构
[1] Chinese Acad Sci, State Key Lab Stem Cell & Reprod Biol, Inst Zool, Beijing 100101, Peoples R China
[2] Chinese Acad Sci, State Key Lab Membrane Biol, Inst Zool, Beijing 100101, Peoples R China
[3] Chinese Acad Sci, Inst Zool, Key Lab Organ Regenerat & Reconstruct, Beijing 100101, Peoples R China
[4] Chinese Acad Sci, Beijing Inst Genom, CAS Key Lab Genom & Precis Med, Beijing 100101, Peoples R China
[5] China Natl Ctr Bioinformat, Beijing 100101, Peoples R China
[6] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
[7] Chinese Acad Sci, Inst Stem Cell & Regenerat, Beijing 100101, Peoples R China
[8] Beijing Inst Stem Cell & Regenerat Med, Beijing 100101, Peoples R China
[9] Capital Med Univ, Adv Innovat Ctr Human Brain Protect, Beijing 100053, Peoples R China
[10] Capital Med Univ, Xuanwu Hosp, Natl Clin Res Ctr Geriatr Disorders, Beijing 100053, Peoples R China
[11] Capital Med Univ, Xuanwu Hosp, Aging Translat Med Ctr, Int Ctr Aging & Canc,Beijing Municipal Geriatr Med, Beijing 100053, Peoples R China
[12] Hainan Med Univ, Hainan Acad Med Sci, Int Ctr Aging & Canc, Haikou 571199, Peoples R China
[13] Aging Biomarker Consortium, Beijing 100101, Peoples R China
[14] Capital Med Univ, Beijing Anzhen Hosp, Beijing Inst Heart Lung & Blood Vessel Dis, Beijing 100029, Peoples R China
来源
基金
北京市自然科学基金; 中国国家自然科学基金;
关键词
D O I
10.1093/procel/pwae035
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页数:7
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