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Changes in Emergency Department Pediatric Readiness and Mortality
被引:1
|作者:
Newgard, Craig D.
[1
]
Rakshe, Shauna
[2
]
Salvi, Apoorva
[1
]
Lin, Amber
[1
]
Cook, Jennifer N. B.
[1
]
Gausche-Hill, Marianne
[3
]
Kuppermann, Nathan
[4
,5
]
Goldhaber-Fiebert, Jeremy D.
[6
]
Burd, Randall S.
[7
]
Malveau, Susan
[1
]
Jenkins, Peter C.
[8
]
Stephens, Caroline Q.
[9
]
Glass, Nina E.
[10
]
Hewes, Hilary
[11
]
Mann, N. Clay
[11
]
Ames, Stefanie G.
[11
]
Fallat, Mary
[12
]
Jensen, Aaron R.
[13
]
Ford, Rachel L.
[14
]
Child, Angela
[11
]
Carr, Brendan
[15
]
Lang, Kendrick
[1
]
Buchwalder, Kyle
[1
]
Remick, Katherine E.
[16
,17
]
机构:
[1] Oregon Hlth & Sci Univ, Ctr Policy & Res Emergency Med, Dept Emergency Med, 181 SW Sam Jackson Park Rd,Mail Code CR-11, Portland, OR 97239 USA
[2] Oregon Hlth & Sci Univ, Knight Canc Inst Biostat Shared Resource, Portland, OR USA
[3] Harbor UCLA Med Ctr, Los Angeles Cty Emergency Med Serv, Torrance, CA USA
[4] Univ Calif Sacramento, Davis Sch Med, Dept Emergency Med, Sacramento, CA USA
[5] Univ Calif Davis, Sch Med, Dept Pediat, Sacramento, CA USA
[6] Stanford Univ, Ctr Hlth Policy Primary Care & Outcomes Res, Dept Med, Sch Med, Palo Alto, CA USA
[7] Childrens Natl Hosp, Ctr Surg Care, Div Trauma & Burn Surg, Washington, DC USA
[8] Indiana Univ Sch Med, Dept Surg, Indianapolis, IN USA
[9] Univ Calif San Francisco, Dept Surg, San Francisco, CA USA
[10] Rutgers New Jersey Med Sch, Dept Surg, Newark, NJ USA
[11] Univ Utah, Sch Med, Dept Pediat, Salt Lake City, UT USA
[12] Univ Louisville, Norton Childrens Hosp, Sch Med, Dept Surg, Louisville, KY USA
[13] Univ Calif San Francisco, Benioff Childrens Hosp, Dept Surg, San Francisco, CA USA
[14] Oregon Hlth Author, Oregon Emergency Med Serv Children Program, Portland, OR USA
[15] Icahn Sch Med Mt Sinai, Dept Emergency Med, New York, NY USA
[16] Univ Texas Austin, Dell Med Sch, Dept Pediat, Austin, TX USA
[17] Univ Texas Austin, Med Sch, Dept Surg, Austin, TX USA
关键词:
PROBABILISTIC LINKAGE;
MULTIPLE IMPUTATION;
D O I:
10.1001/jamanetworkopen.2024.22107
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Importance High emergency department (ED) pediatric readiness is associated with improved survival, but the impact of changes to ED readiness is unknown. Objective To evaluate the association of changes in ED pediatric readiness at US trauma centers between 2013 and 2021 with pediatric mortality. Design, Setting, and Participants This retrospective cohort study was performed from January 1, 2012, through December 31, 2021, at EDs of trauma centers in 48 states and the District of Columbia. Participants included injured children younger than 18 years with admission or injury-related death at a participating trauma center, including transfers to other trauma centers. Data analysis was performed from May 2023 to January 2024. Exposure Change in ED pediatric readiness, measured using the weighted Pediatric Readiness Score (wPRS, range 0-100, with higher scores denoting greater readiness) from national assessments in 2013 and 2021. Change groups included high-high (wPRS >= 93 on both assessments), low-high (wPRS <93 in 2013 and wPRS >= 93 in 2021), high-low (wPRS >= 93 in 2013 and wPRS <93 in 2021), and low-low (wPRS <93 on both assessments). Main Outcomes and Measures The primary outcome was lives saved vs lost, according to ED and in-hospital mortality. The risk-adjusted association between changes in ED readiness and mortality was evaluated using a hierarchical, mixed-effects logistic regression model based on a standardized risk-adjustment model for trauma, with a random slope-random intercept to account for clustering by the initial ED. Results The primary sample included 467 932 children (300 024 boys [64.1%]; median [IQR] age, 10 [4 to 15] years; median [IQR] Injury Severity Score, 4 [4 to 15]) at 417 trauma centers. Observed mortality by ED readiness change group was 3838 deaths of 144 136 children (2.7%) in the low-low ED group, 1804 deaths of 103 767 children (1.7%) in the high-low ED group, 1288 deaths of 64 544 children (2.0%) in the low-high ED group, and 2614 deaths of 155 485 children (1.7%) in the high-high ED group. After risk adjustment, high-readiness EDs (persistent or change to) had 643 additional lives saved (95% CI, -328 to 1599 additional lives saved). Low-readiness EDs (persistent or change to) had 729 additional preventable deaths (95% CI, -373 to 1831 preventable deaths). Secondary analysis suggested that a threshold of wPRS 90 or higher may optimize the number of lives saved. Among 716 trauma centers that took both assessments, the median (IQR) wPRS decreased from 81 (63 to 94) in 2013 to 77 (64 to 93) in 2021 because of reductions in care coordination and quality improvement. Conclusions and Relevance Although the findings of this study of injured children in US trauma centers were not statistically significant, they suggest that trauma centers should increase their level of ED pediatric readiness to reduce mortality and increase the number of pediatric lives saved after injury.
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