Duck enteritis virus UL7 is a late gene and the UL7-encoded protein co-localizes with pUL51

被引：0

作者：

Huang, Jie ^{[1
,2
,3
]}

Wang, Mingshu ^{[1
,2
,3
]}

Cheng, Anchun ^{[1
,2
,3
]}

Tian, Bin ^{[1
,2
,3
]}

Ou, Xuming ^{[1
,2
,3
]}

Wu, Ying ^{[1
,2
,3
]}

Yang, Qiao ^{[1
,2
,3
]}

Sun, Di ^{[1
,2
,3
]}

Zhang, Shaqiu ^{[1
,2
,3
]}

Mao, Sai ^{[1
,2
,3
]}

Zhao, Xinxin ^{[1
,2
,3
]}

Huang, Juan ^{[1
,2
,3
]}

Gao, Qun ^{[1
,2
,3
]}

Zhu, Dekang ^{[1
,2
,3
]}

Jia, Renyong ^{[1
,2
,3
]}

Chen, Shun ^{[1
,2
,3
]}

Liu, Mafeng ^{[1
,2
,3
]}

机构：

[1] Sichuan Agr Univ, Inst Prevent Vet Med, Chengdu, Sichuan, Peoples R China

[2] Sichuan Agr Univ, Key Lab Anim Dis & Human Hlth Sichuan Prov, Chengdu, Sichuan, Peoples R China

[3] Sichuan Agr Univ, Coll Vet Med, Avian Dis Res Ctr, Chengdu, Sichuan, Peoples R China

来源：

ACTA VIROLOGICA | 2024年 / 68卷

关键词：

duck enteritis virus; UL7; protein; UL51; late gene; co-localization; IDENTIFICATION; REPLICATION; INTERACTS; PRODUCT; PLAGUE; PLAYS;

D O I：

10.3389/av.2024.12023

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Background Duck enteritis virus (DEV) belongs to Alphaherpesvirinae; little is known about the DEV UL7 gene and its encoded protein. This study examined the molecular characteristics of DEV pUL7 in vitro and determined whether DEV pUL7 co-localizes with pUL51.Results The results showed that UL7 can be regarded as a late gene. Moreover, immunofluorescence assay revealed that pUL7 was located around the perinuclear cytoplasmic region and co-localized with pUL51 in the cytoplasm and nucleus after transfection into duck embryo fibroblast cells (DEFs).Conclusion In conclusion, we identified the molecular characteristics of the DEV UL7 gene, which is a late gene, and the co-localization of its encoded protein with pUL51 in transfected DEFs, enriching our understanding of pUL7 and future research directions.

引用

页数：10

共 32 条

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Waqas Ahmad
Yingying Li
Yidi Guo
Xinyu Wang
Ming Duan
Zhenhong Guan
Zengshan Liu
Maolin Zhang
Virologica Sinica, 2017, 32 (03) : 207 - 215
[32] Rabies virus co-localizes with early (Rab5) and late (Rab7) endosomal proteins in neuronal and SH-SY5Y cells
Ahmad, Waqas
Li, Yingying
Guo, Yidi
Wang, Xinyu
Duan, Ming
Guan, Zhenhong
Liu, Zengshan
Zhang, Maolin
VIROLOGICA SINICA, 2017, 32 (03) : 207 - 215

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