Duck enteritis virus UL7 is a late gene and the UL7-encoded protein co-localizes with pUL51

被引:0
|
作者
Huang, Jie [1 ,2 ,3 ]
Wang, Mingshu [1 ,2 ,3 ]
Cheng, Anchun [1 ,2 ,3 ]
Tian, Bin [1 ,2 ,3 ]
Ou, Xuming [1 ,2 ,3 ]
Wu, Ying [1 ,2 ,3 ]
Yang, Qiao [1 ,2 ,3 ]
Sun, Di [1 ,2 ,3 ]
Zhang, Shaqiu [1 ,2 ,3 ]
Mao, Sai [1 ,2 ,3 ]
Zhao, Xinxin [1 ,2 ,3 ]
Huang, Juan [1 ,2 ,3 ]
Gao, Qun [1 ,2 ,3 ]
Zhu, Dekang [1 ,2 ,3 ]
Jia, Renyong [1 ,2 ,3 ]
Chen, Shun [1 ,2 ,3 ]
Liu, Mafeng [1 ,2 ,3 ]
机构
[1] Sichuan Agr Univ, Inst Prevent Vet Med, Chengdu, Sichuan, Peoples R China
[2] Sichuan Agr Univ, Key Lab Anim Dis & Human Hlth Sichuan Prov, Chengdu, Sichuan, Peoples R China
[3] Sichuan Agr Univ, Coll Vet Med, Avian Dis Res Ctr, Chengdu, Sichuan, Peoples R China
关键词
duck enteritis virus; UL7; protein; UL51; late gene; co-localization; IDENTIFICATION; REPLICATION; INTERACTS; PRODUCT; PLAGUE; PLAYS;
D O I
10.3389/av.2024.12023
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Background Duck enteritis virus (DEV) belongs to Alphaherpesvirinae; little is known about the DEV UL7 gene and its encoded protein. This study examined the molecular characteristics of DEV pUL7 in vitro and determined whether DEV pUL7 co-localizes with pUL51.Results The results showed that UL7 can be regarded as a late gene. Moreover, immunofluorescence assay revealed that pUL7 was located around the perinuclear cytoplasmic region and co-localized with pUL51 in the cytoplasm and nucleus after transfection into duck embryo fibroblast cells (DEFs).Conclusion In conclusion, we identified the molecular characteristics of the DEV UL7 gene, which is a late gene, and the co-localization of its encoded protein with pUL51 in transfected DEFs, enriching our understanding of pUL7 and future research directions.
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页数:10
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