Incidence of Acute Kidney Injury and Mortality Post Successful Cardiac Surgery in a Kashmiri Cohort: A Prospective Comparison of the RIFLE and KDIGO Criteria
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Jan, Hadiya
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DIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Dehra Dun, IndiaDIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Dehra Dun, India
Jan, Hadiya
[1
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Ram, Chetan
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DIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Pharmacol, Dehra Dun, IndiaDIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Dehra Dun, India
Ram, Chetan
[2
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Bhat, Mohammad A.
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Sheri Kashmir Inst Med Sci, Nephrol, Srinagar, IndiaDIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Dehra Dun, India
Bhat, Mohammad A.
[3
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Ganie, Farooq A.
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Sheri Kashmir Inst Med Sci, Cardiovasc Thorac Surg, Srinagar, IndiaDIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Dehra Dun, India
Ganie, Farooq A.
[4
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Singhal, Manmohan
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DIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Pharmacol, Dehra Dun, IndiaDIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Dehra Dun, India
Singhal, Manmohan
[2
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Arora, Mandeep K.
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DIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Pharmacol, Dehra Dun, IndiaDIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Dehra Dun, India
Arora, Mandeep K.
[2
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机构:
[1] DIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Dehra Dun, India
[2] DIT Univ, Fac Pharm, Sch Pharmaceut & Populat Hlth Informat, Pharmacol, Dehra Dun, India
[3] Sheri Kashmir Inst Med Sci, Nephrol, Srinagar, India
[4] Sheri Kashmir Inst Med Sci, Cardiovasc Thorac Surg, Srinagar, India
Background and objectives In critically ill patients, acute kidney injury (AKI) influences mortality and morbidity. Few studies have looked at mortality and the frequency of AKI following successful heart and thoracic operations. The current study investigates the association between AKI and mortality rates among patients undergoing post-cardiac surgery care within the Cardiology & Cardio Vascular Thoracic Surgery (CVTS) Intensive Care Unit (ICU). Methodology In this prospective research, 124 patients who underwent successful cardiovascular and thoracic procedures between June 2022 and June 2023 were admitted to the CVTS ICU. To determine mortality, we contrasted the two scoring methods, Kidney Disease-Improving Global Outcomes (KDIGO) and Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease (RIFLE). Results Based on the KDIGO criteria, AKI was identified in 37.90% (n = 47) of the patients, and it was identified in 15.32% (n = 19) of the patients utilizing RIFLE. Notably, patients diagnosed with AKI using either the RIFLE criteria or KDIGO criteria exhibited considerably higher mortality rates (p< 0.001). Receiver operating characteristic (ROC) analysis demonstrated the effectiveness of both scoring systems in identifying mortality (area under the ROC curve for RIFLE = 0.224 and KDIGO = 0.150). Conclusion Post-cardiac surgery, AKI escalates both mortality and morbidity rates. Despite KDIGO detecting more severe renal injury and mortality, both scoring systems exhibit comparable sensitivity and specificity in predicting death among patients undergoing various cardiovascular and thoracic procedures.