Familial Acute Promyelocytic Leukemia: A Case Report and Review of the Literature

被引：0

作者：

Yang, Mingqi ^{[1
,2
]}

Bai, Lian ^{[3
]}

Ma, Yunju ^{[1
,2
]}

Cao, Xuanqi ^{[1
,2
]}

Cui, Qingya ^{[1
,2
]}

Wu, Depei ^{[1
,2
]}

Tang, Xiaowen ^{[1
,2
]}

机构：

[1] Soochow Univ, Jiangsu Inst Hematol, Natl Clin Res Ctr Hematol Dis, Affiliated Hosp 1, Suzhou, Peoples R China

[2] Soochow Univ, Inst Blood & Marrow Transplantat, Collaborat Innovat Ctr Hematol, Suzhou, Peoples R China

[3] Canglang Hosp Suzhou, Suzhou, Peoples R China

来源：

ONCOTARGETS AND THERAPY | 2024年 / 17卷

基金：

中国国家自然科学基金;

关键词：

familial; acute promyelocytic leukemia; APL differentiation syndrome; hereditary predisposition; germline mutation; TERM-FOLLOW-UP; ARSENIC TRIOXIDE; PREDISPOSITION;

D O I：

10.2147/OTT.S482781

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Acute promyelocytic leukemia (APL) is characterized by a reciprocal translocation t (15;17) (q24;q21), which leads to the fusion of PML and RAR alpha genes known as PML-RAR alpha fusion. A few cases of potentially hereditary leukemia-related genes in APL have been reported, but no instances of familial aggregation of APL have been documented. Here, we describe a family in whom two members successively affected by APL The potential familial association observed in these two cases of APL highlights the need for further investigation and more definitive genetic lineage tracing in order to understand the genetic basis of this disease.

引用

页码：733 / 738

页数：6

共 50 条

[1] Acute promyelocytic leukemia with myelofibrosis A case report and literature review
Xiao, Mengyu
Qin, Ling
Niu, Xiaona
Zhou, Pan
Niu, Junwei
Wei, Shengjie
Li, Dan
Dou, Liurui
Zhang, Wanjun
Zhang, Lei
Sun, Kai
Bai, Yanliang
[J]. MEDICINE, 2021, 100 (13) : E24567
[2] ACUTE PROMYELOCYTIC LEUKEMIA IN CHILDHOOD - REPORT OF A CASE WITH A REVIEW OF THE LITERATURE
ENGELHARD, D
YATZIV, S
RACHMILEWITZ, EA
POLLIACK, A
[J]. ACTA HAEMATOLOGICA, 1979, 62 (5-6) : 282 - 284
[3] Acute promyelocytic leukemia with secondary myelofibrosis - Case report and review of the literature
Dutta, P
Hasan, S
Bhattacharyya, J
Kumar, R
Mahapatra, M
Saxena, R
Tyagi, S
Sazawal, S
Pati, HP
[J]. AMERICAN JOURNAL OF HEMATOLOGY, 2006, 81 (06) : 476 - 477
[4] Therapy-Related Acute Promyelocytic Leukemia: A Case Report and a Review of Literature
Foster, Dawson
Nair, Hari K.
Robbins, Katherine
Rajeh, Nabeel
[J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (07)
[5] PEDIATRIC ACUTE PROMYELOCYTIC LEUKEMIA AND FANCONI ANEMIA: CASE REPORT AND LITERATURE REVIEW
Freycon, Claire
Sepulchre, Edith
Lavallee, Vincent-Philippe
Goudie, Catherine
Vezina, Catherine
[J]. PEDIATRIC BLOOD & CANCER, 2023, 70 : S550 - S551
[6] Treatment of acute promyelocytic leukemia in the very elderly: Case report and review of the literature
Sham, RL
Tallman, MS
[J]. LEUKEMIA RESEARCH, 2004, 28 (12) : 1347 - 1350
[7] Meningeal relapse in a patient with acute promyelocytic leukemia a case report and review of the literature
Bae, SH
Ryoo, HM
Cho, HS
Lee, JL
Lee, KH
Hyun, MS
[J]. JOURNAL OF KOREAN MEDICAL SCIENCE, 2004, 19 (02) : 311 - 314
[8] Pediatric acute promyelocytic leukemia and Fanconi anemia: Case report and literature review
Freycon, Claire
Sepulchre, Edith
Lavallee, Vincent-Philippe
Mitchell, David
Macmillan, Margaret L.
Vezina, Catherine
Goudie, Catherine
[J]. CLINICAL GENETICS, 2024, 106 (02) : 193 - 198
[9] Case Report: Extramedullary Acute Promyelocytic Leukemia: An Unusual Case and Mini-Review of the Literature
Harrer, Dennis Christoph
Lueke, Florian
Einspieler, Ingo
Menhart, Karin
Hellwig, Dirk
Utpatel, Kirsten
Herr, Wolfgang
Reichle, Albrecht
Heudobler, Daniel
[J]. FRONTIERS IN ONCOLOGY, 2022, 12
[10] Transformation from polycythemia vera to acute promyelocytic leukemia: Case report and literature review
Li, Wen-Wen
Sui, Xiu-Fang
Fan, Shuang
Xu, Hong
Wang, Cheng-Lei
Wang, Fei-Ying
Mo, Xiao-Dong
[J]. MEDICINE, 2022, 101 (32) : E30064

← 1 2 3 4 5 →