Simultaneous Loss of Podocyte Insulin Receptor (IR) and Insulin-Like Growth Factor 1 Receptor (IGF1R) Is Detrimental and Associated with Spliceosome Dysfunction

被引:0
|
作者
Hurcombe, Jenny [1 ]
Dayalan, Lusyan [1 ]
Barrington, Fern [1 ]
Ni, Lan [1 ]
Brinkkoetter, Paul T. [2 ]
Holzenberger, Martin [3 ]
Welsh, Gavin I. [1 ]
Coward, Richard [1 ]
机构
[1] Univ Bristol, Bristol, Avon, England
[2] Uniklin Koln, Cologne, Germany
[3] INSERM, Paris, France
来源
关键词
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
PO1690
引用
收藏
页码:526 / 526
页数:1
相关论文
共 50 条
  • [21] The Insulin-Like Growth Factor (IGF) Receptor Type 1 (IGF1R) as an Essential Component of the Signalling Network Regulating Neurogenesis
    Alexander Annenkov
    Molecular Neurobiology, 2009, 40 : 195 - 215
  • [22] The Insulin-Like Growth Factor (IGF) Receptor Type 1 (IGF1R) as an Essential Component of the Signalling Network Regulating Neurogenesis
    Annenkov, Alexander
    MOLECULAR NEUROBIOLOGY, 2009, 40 (03) : 195 - 215
  • [23] Targeting the Insulin-like Growth Factor 1 (IGF1R) and Insulin (IR) Receptor with a Dual IGF1R/IR Inhibitor, OSI-906, to Potentiate mTOR Inhibitor Effects in Exeperimental Models of Hepatocellular Carcinoma (HOC)
    Pivonello, Claudia
    Negri, Mariarosaria
    De Martino, Maria Cristina
    Napolitano, Maria
    de Angelis, Cristina
    Izzo, Francesco
    Colao, Annamaria
    Hofland, Leo J.
    Pivonello, Rosario
    ENDOCRINE REVIEWS, 2014, 35 (03)
  • [24] Low activation of Insulin-like Growth Factor 1-Receptor (IGF1R) is associated with local recurrence in early breast carcinoma
    Gloria Peiró
    Susana Benlloch
    Laura Sánchez-Tejada
    Encarna Adrover
    Enrique Lerma
    Francisca M. Peiró
    José Sánchez-Payá
    F. Ignacio Aranda
    Breast Cancer Research and Treatment, 2009, 117 : 433 - 441
  • [25] Low activation of Insulin-like Growth Factor 1-Receptor (IGF1R) is associated with local recurrence in early breast carcinoma
    Peiro, Gloria
    Benlloch, Susana
    Sanchez-Tejada, Laura
    Adrover, Encarna
    Lerma, Enrique
    Peiro, Francisca M.
    Sanchez-Paya, Jose
    Ignacio Aranda, F.
    BREAST CANCER RESEARCH AND TREATMENT, 2009, 117 (02) : 433 - 441
  • [26] A common polymorphism in exon 16 of the human insulin-like growth factor-1 receptor gene (IGF1R)
    AbuAmero, S
    Preece, M
    Wakeling, E
    Moore, G
    Stanier, P
    MOLECULAR AND CELLULAR PROBES, 1997, 11 (05) : 381 - 383
  • [27] The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript
    Bohula, EA
    Salisbury, AJ
    Sohail, M
    Playford, MP
    Riedemann, J
    Southern, EM
    Macaulay, VM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (18) : 15991 - 15997
  • [28] TRINUCLEOTIDE REPEAT POLYMORPHISM AT THE HUMAN INSULIN-LIKE GROWTH FACTOR-I RECEPTOR GENE (IGF1R)
    MELONI, R
    FOUGEROUSSE, F
    ROUDAUT, C
    BECKMANN, JS
    NUCLEIC ACIDS RESEARCH, 1992, 20 (06) : 1427 - 1427
  • [29] Profiling the type I insulin-like growth factor receptor (IGF1R) pathway regulated metastasis signature
    Sarver, Aaron
    Sachdev, Deepali
    MOLECULAR CANCER THERAPEUTICS, 2009, 8 (12)
  • [30] Insulin growth factor 1 like receptor (IGF-1R)
    Iyer, Gopal
    Price, James
    Bourgeois, Shay
    Armstrong, Eric
    Huang, Shyhmin
    Harari, Paul M.
    BMC CANCER, 2016, 16