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Synthesis and crystal structure of a tripeptide comprising a centrally placed non-coded aromatic γ-amino acid
被引:0
|作者:
Das, Purak
[2
]
Das, Suven
[2
]
Dutta, Arpita
[1
]
机构:
[1] Rishi Bankim Chandra Evening Coll, Dept Chem, 24-Parganas N, Naihati 743165, India
[2] Rishi Bankim Chandra Coll Women, Dept Chem, 24-Parganas N, Naihati 743165, India
来源:
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-CRYSTALLINE MATERIALS
|
2024年
/
239卷
/
9-10期
关键词:
5-aminoisophthalic acid;
aromatic gamma-amino acid;
tripeptide;
self-assembly;
PEPTIDES;
FOLDAMERS;
RESIDUE;
DESIGN;
IMPACT;
HELIX;
D O I:
10.1515/zkri-2024-0095
中图分类号:
O7 [晶体学];
学科分类号:
0702 ;
070205 ;
0703 ;
080501 ;
摘要:
A protected tripeptide Boc-L-Leu-5-AIA-Aib-OMe was synthesized where 5-aminoisophthalic acid (5-AIA), a rigid non-coded aromatic gamma-amino acid is incorporated as central residue. The single crystal X-ray diffraction study indicates that the peptide self-assembles into supramolecular sheet through intermolecular hydrogen bonding interaction N-H & ctdot;O and pi<middle dot><middle dot><middle dot>pi interaction.
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页码:339 / 343
页数:5
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