Synthesis and crystal structure of a tripeptide comprising a centrally placed non-coded aromatic γ-amino acid

被引：0
|
作者：
Das, Purak [2 ]
Das, Suven [2 ]
Dutta, Arpita [1 ]
机构：
[1] Rishi Bankim Chandra Evening Coll, Dept Chem, 24-Parganas N, Naihati 743165, India
[2] Rishi Bankim Chandra Coll Women, Dept Chem, 24-Parganas N, Naihati 743165, India
来源：
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-CRYSTALLINE MATERIALS | 2024年 / 239卷 / 9-10期
关键词：
5-aminoisophthalic acid; aromatic gamma-amino acid; tripeptide; self-assembly; PEPTIDES; FOLDAMERS; RESIDUE; DESIGN; IMPACT; HELIX;
D O I：
10.1515/zkri-2024-0095
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
A protected tripeptide Boc-L-Leu-5-AIA-Aib-OMe was synthesized where 5-aminoisophthalic acid (5-AIA), a rigid non-coded aromatic gamma-amino acid is incorporated as central residue. The single crystal X-ray diffraction study indicates that the peptide self-assembles into supramolecular sheet through intermolecular hydrogen bonding interaction N-H & ctdot;O and pi<middle dot><middle dot><middle dot>pi interaction.
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收藏
页码：339 / 343
页数：5
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