Post-Traumatic Stress Disorder and Risk of Parkinson's Disease in a Veteran Cohort

被引：0

作者：

Weaver, Frances M. ^{[1
,2
]}

Cao, Lishan ^{[1
]}

Stroupe, Kevin T. ^{[1
,2
]}

Gonzalez, Beverly ^{[3
]}

Brown, Ethan ^{[4
]}

Colletta, Kalea ^{[5
]}

Tanner, Caroline M. ^{[4
,7
]}

Goldman, Samuel M. ^{[6
,7
]}

机构：

[1] Edward Hines Jr VA Hosp, Ctr Innovat Complex Chron Healthcare CINCCH, Hines, IL 60141 USA

[2] Loyola Univ, Parkinson Sch Hlth Sci & Publ Hlth, Maywood, IL USA

[3] Edward Hines Jr VA Hosp, Cooperat Studies Coordinating Ctr, Hines, IL USA

[4] Univ Calif San Francisco, Weill Inst Neurosci, Dept Neurol, San Francisco, CA USA

[5] Edward Hines Jr VA Hosp, Neurol Serv, Hines, IL USA

[6] Univ Calif San Francisco, Div Occupat Environm & Climate Med, San Francisco, CA USA

[7] San Francisco VA Hlth Care Syst, Res Serv, San Francisco, CA USA

来源：

JOURNAL OF PARKINSONS DISEASE | 2024年 / 14卷 / 06期

关键词：

PTSD; Parkinson's disease; Veterans; epidemiology; stress; PREVALENCE;

D O I：

10.3233/JPD-240098

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

. Post-traumatic stress disorder (PTSD) may be a risk factor for Parkinson's disease (PD). We examined the relation between PTSD and PD in a cohort of 158,122 Veterans who had any Veterans Health Administration (VHA) or Medicare health care utilization between 10/1/1999-2/17/2021. Using a nested case-control design we matched 10 controls to each Veteran with PD by sex, race, and rank. In conditional logistic regression models adjusted for camp and smoking, a PTSD diagnosis was significantly associated with PD (OR = 1.35; p = 0.0002); odds were higher if PTSD was coded before PD (OR =1.53, p < 0.0001). PTSD may be a risk factor for PD.

引用

页码：1265 / 1269

页数：5

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