Modakafusp alfa shows intratumoral immune pharmacodynamics (PD) in a subset of patients (pts) in a phase 1b study in advanced/metastatic solid tumors

被引：0
|
作者：
Saggu, Gurpanna
Markman, Janet L.
Lee, Min Young
Dunbar, Faith
Joshi, Adarsh
Wang, Shining
Collins, Sabrina
机构：
来源：
CANCER RESEARCH | 2024年 / 84卷 / 07期
关键词：
D O I：
10.1158/1538-7445.AM2024-CT065
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
CT065
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Phase 1b study of multiple dosing schedules of pazopanib in combination with epirubicin or doxorubicin in patients with advanced solid tumors
    Fasolo, A.
    Sessa, C.
    Vigano, L.
    Locatelli, A.
    Hess, D.
    Homicsko, K.
    Capri, G.
    Suttle, B.
    Tada, H.
    Gianni, L.
    EUROPEAN JOURNAL OF CANCER, 2013, 49 : S164 - S164
  • [32] The effect of different dosing regimens of motesanib on the gallbladder: a randomized phase 1b study in patients with advanced solid tumors
    Lee S Rosen
    Lara Lipton
    Timothy J Price
    Neil D Belman
    Ralph V Boccia
    Herbert I Hurwitz
    Joe J Stephenson Jr
    Lori J Wirth
    Sheryl McCoy
    Yong-jiang Hei
    Cheng-Pang Hsu
    Niall C Tebbutt
    BMC Cancer, 13
  • [33] The effect of different dosing regimens of motesanib on the gallbladder: a randomized phase 1b study in patients with advanced solid tumors
    Rosen, Lee S.
    Lipton, Lara
    Price, Timothy J.
    Belman, Neil D.
    Boccia, Ralph V.
    Hurwitz, Herbert I.
    Stephenson, Joe J., Jr.
    Wirth, Lori J.
    Mccoy, Sheryl
    Hei, Yong-jiang
    Hsu, Cheng-Pang
    Tebbutt, Niall C.
    BMC CANCER, 2013, 13
  • [34] A phase 1b study of the ERK inhibitor MK-8353 plus pembrolizumab in patients with advanced solid tumors
    Lakhani, Nehal J.
    Burris III, Howard
    Miller Jr, Wilson H.
    Huang, Mo
    Chen, Lin-Chi
    Siu, Lillian L.
    INVESTIGATIONAL NEW DRUGS, 2024, 42 (05) : 581 - 589
  • [35] A phase 1b, open-label, dose-escalation study to evaluate camidanlumab tesirine (Cami) as monotherapy in patients (pts) with advanced solid tumors.
    Puzanov, Igor
    LoRusso, Patricia
    Papadopoulos, Kyriakos P.
    Chen, Christopher T.
    LeBruchec, Yvan
    He, Xiaomin
    Cousin, Thierry
    Havenith, Karin
    Boni, Joseph
    Bendell, Johanna C.
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [36] A phase 1b/2 study of INCB039110+nab-paclitaxel (N) and gemcitabine (G) in patients (pts) with advanced solid tumors and pancreatic cancer (PC).
    Beatty, Gregory Lawrence
    Shanda, Safi
    Beck, J. Thaddeus
    Uppal, Nikhil Premparkash
    Cohen, Steven J.
    Donehower, Ross C.
    Gabayan, A. Eli
    Assad, Albert
    Switzky, Julie C.
    Zhen, Huiling
    Von Hoff, Daniel D.
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (04)
  • [37] A PHASE 1 STUDY OF IMC-001, A PD-L1 BLOCKER, IN PATIENTS WITH METASTATIC OR LOCALLY ADVANCED SOLID TUMORS
    Keam, Bhumsuk
    Kim, Tae Min
    Oh, Do-Youn
    Ock, Chan-Young
    Kang, Won Ki
    Park, Yeon Hee
    Lee, Jeeyun
    Lee, Ji Hye
    Song, Yun Jeong
    Park, Young Suk
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 : A176 - A176
  • [38] A phase 1/1b study of satraplatin (JM-216) in combination with docetaxel in patients with advanced solid tumors and metastatic castrate-resistant prostate cancer
    Cetnar, Jeremy
    Wilding, George
    McNeel, Douglas
    LoConte, Noelle K.
    McFarland, Thomas A.
    Eickhoff, Jens
    Liu, Glenn
    UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2013, 31 (04) : 436 - 441
  • [39] Phase 1b trial of anti-VEGF/PDGFR vorolanib combined with immune checkpoint inhibitors in patients with advanced solid tumors
    Nusayba A. Bagegni
    Haeseong Park
    Katlyn Kraft
    Maura O-Toole
    Feng Gao
    Saiama N. Waqar
    Lee Ratner
    Daniel Morgensztern
    Siddhartha Devarakonda
    Manik Amin
    Maria Q. Baggstrom
    Chris Liang
    Giovanni Selvaggi
    Andrea Wang-Gillam
    Cancer Chemotherapy and Pharmacology, 2022, 89 : 487 - 497
  • [40] Results of study PX-171-007 a phase 1b/2 study of carfilzomib, a selective proteasome inhibitor, in patients with selected advanced metastatic solid tumors
    Gordon, M.
    Infante, J.
    Papadopoulos, K. P.
    Lee, P.
    Sausville, E.
    Mendelson, D.
    Wong, A. F.
    Vallone, M.
    Rosen, P. J.
    Burris, H.
    EJC SUPPLEMENTS, 2009, 7 (02): : 122 - 123
12345