The Transformation of Neck Unicentric Castleman's Disease to Follicular Dendritic Cell Sarcoma

被引：0
|
作者：
Li, Yingying [1 ]
Shao, Yue [2 ]
Sun, Xiumei [3 ]
Huang, Hai [4 ]
Leng, Xiaochen [5 ]
Wang, Yuliang [2 ]
机构：
[1] Binzhou Med Univ, Dept Otolaryngol Head & Neck Surg, Yantai Affiliated Hosp, Yantai, Peoples R China
[2] Binzhou Med Univ, Dept Oral & Maxillofacial Surg, Yantai Affiliated Hosp, 717 Jinbu St, Yantai 264100, Peoples R China
[3] Binzhou Med Univ, Dept Lab, Yantai Affiliated Hosp, Yantai, Peoples R China
[4] Binzhou Med Univ, Dept Pathol, Yantai Affiliated Hosp, Yantai, Peoples R China
[5] Binzhou Med Univ, Dept Ultrasound Med, Yantai Affiliated Hosp, Yantai, Peoples R China
来源：
LARYNGOSCOPE | 2024年 / 134卷 / 12期
关键词：
follicular dendritic cell sarcoma; malignant transformation; neck; surgery; unicentric Castleman's disease;
D O I：
10.1002/lary.31587
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
A patient with a large neck mass underwent appropriate imaging, routine blood tests, and serological evaluations. The medical history revealed the patient had undergone a lymphadenectomy in the same region 8years ago, and the pathological diagnosis was the hyaline-vascular subtype of unicentric Castleman's disease (UCD). The incisional biopsy and subsequent histopathological and immunohistochemical examination revealed the diagnosis of follicular dendritic cell sarcoma, consistent with the malignant transformation of UCD. UCD is uncommon and the malignant transformation of UCD is extremely rare in the head and neck region. Regional lymph node resection of one or more adjacent regions is the preferred treatment choice. Appropriate treatment procedures for UCD and regular follow-up are essential for a good prognosis.
引用
收藏
页码：4985 / 4987
页数：3
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