Course of myelin oligodendrocyte glycoprotein-associated disease (MOGAD) - a cohort of patients

被引:0
|
作者
Hanakova, P. [1 ,2 ,3 ,4 ]
Danhofer, P. [1 ,2 ]
Dufek, M. [3 ,4 ]
Senkyrik, J. [2 ,5 ]
Kominek, M. [2 ,6 ]
Dominik, P. [2 ,7 ]
Oslejskova, H. [1 ,2 ]
机构
[1] Klin Detske Neurol LF MU, Jihlavska 340-20, Brno 62500, Czech Republic
[2] FN Brno, Jihlavska 340-20, Brno 62500, Czech Republic
[3] 1 Neurol Klin LF MU, Brno, Czech Republic
[4] FN Sv Anny, Brno, Czech Republic
[5] Klin Radiol Nukl Med LF MU, Brno, Czech Republic
[6] Detska Ocni Klin LF MU, Brno, Czech Republic
[7] Klin Detske Anesteziol Resuscitace LF MU, Brno, Czech Republic
关键词
myelin; oligodendrocyte glycoprotein autoimmune demyelinating disorders; CNS; optic neuritis; myelitis; plasmapheresis; PLASMA-EXCHANGE; ANTIBODIES; CHILDREN; AQUAPORIN-4; RITUXIMAB; RESPONSES;
D O I
10.48095/cccsnn2024122
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The aim of this paper is to provide a comprehensive overview of myelin-oligodendrocyte glycoprotein antibody -associated disease (MOGAD) and to provide our own practical experience with the dia gnosis and treatment of this disease. We present a series of seven patients followed prospectively in our department from 1/ 2018 to 2/ 2023. Average age of children at the time of dia gnosis was 11.4 +/- 2.8 years. All patients fulfilled the MOGAD dia gnostic criteria at the time. We present the individual cases and highlight the nature of the course of the disease and the pitfalls of treatment. We discuss acute and chronic therapy and point out the need for further prospective studies in children with MOGAD.
引用
收藏
页码:122 / 131
页数:10
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