Can Microneedles Revolutionize Ocular Drug Delivery?

被引：0
|
作者：
Sahinovic, Merima [1 ]
Tucak-Smajic, Amina [1 ]
Muhamedagic, Kenan [2 ]
Hindija, Lamija [1 ]
Rahic, Ognjenka [1 ]
Hadziabdic, Jasmina [1 ]
Vranic, Edina [1 ]
Cekic, Ahmet [2 ]
机构：
[1] Univ Sarajevo, Fac Pharm, Dept Pharmaceut Technol, Zmaja Od Bosne 8, Sarajevo 71000, Bosnia & Herceg
[2] Univ Sarajevo, Fac Mech Engn, Dept Machinery Prod Engn, Vilsonovo Setaliste 9, Sarajevo 71000, Bosnia & Herceg
来源：
MEDICON 2023 AND CMBEBIH 2023, VOL 1 | 2024年 / 93卷
关键词：
Drug delivery systems; Eye diseases/drug therapy; Microneedles; INSERTION;
D O I：
10.1007/978-3-031-49062-0_46
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
The anterior and posterior segments of the eye are extremely difficult to reach and treat, due to their barrier properties and inaccessibility of the ocular tissues. Given that traditional drug delivery systems, such as topical eye drops, or hypodermic needles, possess many disadvantages such as causing pain, and discomfort or resulting in low drug bioavailability, microneedles (MNs) are recently proposed as minimally invasive drug delivery systems for treating ocular diseases. These systems enable the localization of drugs within the ocular tissue, while on the other hand being painless. Given that MNs will definitely change how eye medication formulations are delivered in the future, this work aimed to summarize the previous studies on the potential of using microneedles as drug delivery systems for treating ocular diseases and outline the future aspect of MNs production technologies.
引用
收藏
页码：425 / 433
页数：9
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