Rhinitis Control and Medication Use in a Real-World Sample of Patients With Persistent Rhinitis or Rhinosinusitis: A Community Pharmacy Study

被引:3
|
作者
Scheire, Sophie [1 ]
Germonpre, Sophie [1 ,3 ]
Mehuys, Els [1 ]
Van Tongelen, Inge [1 ]
De Sutter, An [2 ]
Steurbaut, Stephane [2 ]
Van Hees, Thierry [4 ]
Demarche, Sophie [4 ]
Lahousse, Lies [1 ]
Gevaert, Philippe [5 ]
Boussery, Koen [1 ]
机构
[1] Univ Ghent, Fac Pharmaceut Sci, Pharmaceut Care Unit, Ottergemsesteenweg 460, B-9000 Ghent, Belgium
[2] Univ Ghent, Ctr Family Med, Dept Publ Hlth & Primary Care, Ghent, Belgium
[3] Vrije Univ Brussel, Ctr Pharmaceut Res, Dept Clin Pharmacol & Pharmacotherapy, Jette, Belgium
[4] Univ Liege, Dept Pharm, Liege, Belgium
[5] Univ Ghent, Dept Head & Skin, Upper Airways Res Lab, Ghent, Belgium
关键词
ALLERGIC RHINITIS; ASTHMA CONTROL; ADHERENCE; DISEASE; IMPACT; MANAGEMENT; DIAGNOSIS; VALIDITY; QUALITY; ADULTS;
D O I
10.1016/j.jaip.2024.04.031
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
BACKGROUND: Little is known about rhinitis control in reallife, nor about the contribution of treatment-related and patientrelated factors. OBJECTIVE: This study aimed to examine the level of rhinitis control and rhinitis medication utilization in patients with persistent rhinitis and to identify predictors of rhinitis control. METHODS: A cross-sectional observational study was conducted in patients with persistent rhinitis recruited in community pharmacies. Participants completed the Rhinitis Control Assessment Test, a questionnaire on patient/rhinitis characteristics, and rhinitis medication use. A visual analog scale for nasal symptoms was also completed. Pharmacy dispensing data were used to calculate adherence to intranasal glucocorticoids. Nasal spray technique was evaluated using a standardized checklist. Predictors of rhinitis control were explored using a linear regression model. RESULTS: A total of 1,514 patients, recruited in 215 pharmacies, participated in the study (mean age 48.7 y, 62% female). Almost 60% exhibited suboptimal rhinitis control (Rhinitis Control Assessment Test pound 21 of 30). A 50-mm cut-off on the visual analog scale yielded 78.1% sensitivity to identify suboptimal rhinitis control. Participants most frequently used intranasal glucocorticoids (55.6%) and intranasal decongestants (47.4%). Only 10.3% of current nasal spray users demonstrated perfect technique. More than half (54.8%) of glucocorticoid users were identified as active asthma, and use of oral/intranasal decongestants or nasal saline were identified as predictors of worse rhinitis control. CONCLUSIONS: Suboptimal rhinitis control was common in this real-life sample of persistent rhinitis patients. Improving use of rhinitis medication may be key to increase disease con
引用
收藏
页码:1865 / 1876.e6
页数:18
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