Recent advances in TBHP-promoted heterocyclic ring construction via annulation/cyclization

被引：1

作者：

Varala, Ravi ^{[1
,2
]}

Seema, Vittal ^{[3
]}

Amanullah, Mohammed ^{[4
]}

Alam, Mohammed Mujahid ^{[5
]}

机构：

[1] Scrips Pharm, Hyderabad 500076, Telangana, India

[2] INTI Int Univ, Nilai, Malaysia

[3] RGUKT Basar, Dept Chem, Mudhole, Telangana, India

[4] King Khalid Univ, Coll Med, Dept Clin Biochem, Abha, Saudi Arabia

[5] King Khalid Univ, Coll Sci, Dept Chem, Abha, Saudi Arabia

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2024年 / 61卷 / 08期

关键词：

DERIVATIVES; PYRAZOLE; DESIGN; THIAZOLE; INHIBITION; CANCER;

D O I：

10.1002/jhet.4852

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

One of the most often utilized hydroperoxides in an array of oxidation strategies is tert-butyl hydroperoxide (tBuOOH, TBHP). The key reasons for rising utility of TBHP are its low cost, environmental friendliness, high efficiency, and ability to replace hazardous or rare heavy metal oxidants. In this sexennial update, we concisely and critically discussed the applications of TBHP in heterocyclic ring formations starting from 2018 to date. Merits and demerits of its utility, scope of a synthetic organic transformation along with mechanistic logistics are the key features of this review.

引用

页码：1269 / 1298

页数：30

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