Recurrence and Carcinogenetic Rates of Colorectal Polyps

被引:0
|
作者
Stoian, Marilena [1 ,2 ]
Becheanu, Gabriel [3 ,4 ]
Balescu, Irina [5 ]
Eftimie, Mihai [6 ,7 ]
Petrea, Sorin [6 ,8 ]
Diaconu, Camelia [1 ,9 ]
Gaspar, Bogdan [6 ,10 ]
Pop, Lucian [11 ,12 ]
Varlas, Valentin [11 ,13 ]
Hasegan, Adrian [14 ]
Martac, Cristina [15 ]
Bolca, Ciprian [16 ,17 ,18 ]
Stroescu, Cezar [7 ]
Zgura, Anca [19 ,20 ]
Bacalbasa, Nicolae [6 ,7 ]
机构
[1] Carol Davila Univ Med & Pharm, Dept Internal Med, Bucharest, Romania
[2] Dr Ion Cantacuzino Clin Hosp, Dept Internal Med, Bucharest, Romania
[3] Victor Babes Natl Inst Pathol, Dept Histopathol & Immunohistochem, Bucharest, Romania
[4] Fundeni Clin Inst, Dept Pathol Gastroenterol & Hepatol, Bucharest, Romania
[5] Carol Davila Univ Med & Pharm, Bucharest, Romania
[6] Carol Davila Univ Med & Pharm, Dept Surg, Bucharest, Romania
[7] Fundeni Clin Inst, Ctr Excellence Translat Med, Dept Visceral Surg, Bucharest, Romania
[8] Ion Cantacuzino Clin Hosp, Dept Surg, Bucharest, Romania
[9] Floreasca Clin Emergency Hosp, Dept Internal Med, Bucharest, Romania
[10] Floreasca Clin Emergency Hosp, Dept Visceral Surg, Bucharest, Romania
[11] Carol Davila Univ Med & Pharm, Dept Obstet & Gynecol, Bucharest, Romania
[12] Natl Inst Mother & Child Care Alessandrescu Rusesc, Dept Obstet & Gynecol, Bucharest, Romania
[13] Filantropia Clin Hosp, Dept Obstet & Gynecol, Bucharest, Romania
[14] Univ Sibiu, Sibiu Emergency Hosp, Fac Med, Dept Urol, Sibiu, Romania
[15] Fundeni Clin Hosp, Dept Anesthesiol, Bucharest, Romania
[16] Marius Nasta Natl Inst Pneumol, Dept Thorac Surg, Bucharest, Romania
[17] Sherbrooke Univ, Fac Med & Hlth Sci, Sherbrooke, PQ, Canada
[18] Charles LeMoyne Hosp, Dept Thorac Surg, Longueuil, PQ, Canada
[19] Prof Dr Al Trestioreanu Oncol Inst, Dept Med Oncol, Bucharest, Romania
[20] Carol Davila Univ Med & Pharm, Dept Med Oncol, Bucharest, Romania
关键词
colorectal polyps; recurrence of colorectal polyps; colorectal cancer; immunohisto chemical tests; colonoscopy; SOCIETY TASK-FORCE; ADENOMA RECURRENCE; FOLLOW-UP; CANCER; RISK; POLYMORPHISMS; MANAGEMENT; RECOMMENDATIONS; SURVEILLANCE; ASSOCIATION;
D O I
10.21614/chirurgia.2024.v.119.i.1.p.21
中图分类号
R61 [外科手术学];
学科分类号
摘要
Aim to determin the recurrence rate of benign recto -colonic polyps in a 5 -year interval, and compare the development rate of intrapolypoid carcinomatous lesions in polypectomized versus nonpolypectomized subjects. Materials and method a group of 77 patients diagnosed with recto -colonic polypoid lesions during the period 2014-2019 underwent colonoscopy at the time of study initiation and then annually during a five-year interval. Result The recurrence rate of polyps increased annually from 5 to 12.5%; the highest rate was noted in the last two years. The five-year cumulative risk of neoplastic lesions was 73% in patients without polypectomy and 20% among those with endoscopic resection (p< 0.05). Comparing the recurrence rate of benign lesions (60%) in patients without neoplastic findings with the recurrence rate of adenomas in patients with benign lesions (40%), a higher risk of recurrence was found in the first category, and seemed to be influenced by the personal history of pre-existing adenomatous lesions. Conclusion an increased risk of colorectal polyps recurrence was reported during five year follow up; moreover, during the first three years an increased risk of malignant transformation was observed among cases in which endoscopic resection was not feasible when compared to those in which complete excision was feasible.
引用
收藏
页码:21 / 35
页数:121
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