A first-in-human, phase 1 study evaluating oral TACC3 inhibitor, AO-252, in advanced solid tumors.

被引：0
|
作者：
Dumbrava, Ecaterina Elena
Kennon, Amber Michelle
Balema, Wintana A.
Lim, Chaemin
Vempati, Sridhar
Stergiopoulos, Sotirios
Richardson, Debra L.
机构：
[1] Univ Texas MD Anderson Canc Ctr, Dept Invest Canc Therapeut, Houston, TX USA
[2] A2A Pharmaceut Inc, New York, NY USA
[3] Univ Oklahoma, Div Gynecol Oncol, Stephenson Canc Ctr, Hlth Sci Ctr, Oklahoma City, OK USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2024年 / 42卷 / 16期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
TPS3176
引用
收藏
页数：1
相关论文
共 50 条
  • [21] First-in-human phase I dose-escalation study of the oral selective C-met inhibitor EMD 1204831 in patients with advanced solid tumors.
    Amin, Hesham M.
    Falchook, Gerald Steven
    Fu, Siqing
    Hong, David S.
    Tsimberidou, Apostolia Maria
    Naing, Aung
    Wheler, Jennifer J.
    Piha-Paul, Sarina Anne
    Janku, Filip
    Klevesath, Manfred B.
    Jego, Virginie
    Johne, Andreas
    Kurzrock, Razelle
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [22] A first-in-human phase 1 dose-escalation trial of the oral HIF-2a inhibitor PT2977 in patients with advanced solid tumors.
    Papadopoulos, Kyriakos P.
    Jonasch, Eric
    Zojwalla, Naseem J.
    Wang, Keshi
    Bauer, Todd Michael
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [23] First-in-human phase 1 study of TAK-931, an oral cell division cycle 7 (CDC7) inhibitor, in patients (pts) with advanced solid tumors.
    Shimizu, Toshio
    Doi, Toshihiko
    Kondo, Shunsuke
    Takahashi, Hideaki
    Yamamoto, Noboru
    Sheldon-Waniga, Emily
    Zhou, Xiaofei
    Bahamon, Brittany
    Li, Hongmei
    Kuboki, Yasutoshi
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [24] A first-in-human phase I study of U3-1287 (AMG 888), a HER3 inhibitor, in patients (pts) with advanced solid tumors.
    Berlin, J.
    Keedy, V. L.
    Janne, P. A.
    Yee, L.
    Rizvi, N. A.
    Jin, X.
    Copigneaux, C.
    Hettmann, T.
    Beaupre, D. M.
    LoRusso, P.
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
  • [25] First-in-human study of oral S 49076, a MET/AXL/FGFR inhibitor, in advanced solid tumors
    Postel-Vinay, S.
    Hollebecque, A.
    Soria, J. -C.
    Balandraud, S.
    Brendel, K.
    Cattan, V.
    Jacquet-Bescond, A.
    Busto, N. Lopez
    Malasse, S.
    Marfai, L.
    Pauly, J.
    Prudkin, L.
    Azaro, A.
    Rodon, J.
    ANNALS OF ONCOLOGY, 2015, 26 : 37 - 37
  • [26] A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors
    Hong, David S.
    Rosen, Peter
    Lockhart, A. Craig
    Fu, Siqing
    Janku, Filip
    Kurzrock, Razelle
    Khan, Rabia
    Amore, Benny
    Caudillo, Isaac
    Deng, Hongjie
    Hwang, Yuying C.
    Loberg, Robert
    Ngarmchamnanrith, Gataree
    Beaupre, Darrin M.
    Lee, Peter
    ONCOTARGET, 2015, 6 (21) : 18693 - 18706
  • [27] First-in-human phase 1/2 dose escalation and expansion study evaluating first-in-class eIF4A inhibitor zotatifin in patients with solid tumors.
    Meric-Bernstam, Funda
    Sharma, Manish
    Sommerhalder, David
    Skeel, Roland T.
    El-Khoueiry, Anthony B.
    Caswell-Jin, Jennifer Lee
    Patel, Premal H.
    Rosen, Ezra
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [28] A first-in-human phase I study of CZ48, a lactone ring protected oral camptothecin, in patients with advanced solid tumors.
    Mahalingam, Devalingam
    Shaheen, Montaser F.
    Sarantopoulos, John
    Weitman, Steven
    Giovanella, Beppino C.
    Cao, Zhisong
    Coil, Douglas
    Markides, Constantine
    Liu, Lucy
    Verschraegen, Claire F.
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [29] First-in-human, Pharmacokinetic and Pharmacodynamic Phase I Study of Resminostat, an Oral Histone Deacetylase Inhibitor, in Patients with Advanced Solid Tumors
    Brunetto, Andre T.
    Ang, Joo Ern
    Lal, Rohit
    Olmos, David
    Molife, L. Rhoda
    Kristeleit, Rebecca
    Parker, Ann
    Casamayor, Isabel
    Olaleye, Muyibat
    Mais, Anna
    Hauns, Bernhard
    Strobel, Vera
    Hentsch, Bernd
    de Bono, Johann S.
    CLINICAL CANCER RESEARCH, 2013, 19 (19) : 5494 - 5504
  • [30] A phase 1 study of oral navelbine in patients with advanced solid tumors.
    Rajdev, L
    Dai, Q
    Mani, S
    Goldberg, G
    Baker, C
    Hoschander, S
    Sparano, J
    CLINICAL CANCER RESEARCH, 2003, 9 (16) : 6137S - 6137S
12345