Biologics Approaches-When, Why, and How?

被引：0
|
作者：
Stokes, Daniel J. [1 ]
Felan, Nicholas A. [2 ]
McQuivey, Kade S. [1 ]
McGinley, Beau M. [1 ]
Frank, Rachel M. [1 ]
机构：
[1] Univ Colorado, Sch Med, Dept Orthopaed Surg, Aurora, CO USA
[2] Univ Colorado, Colorado State Univ, Dept Orthopaed Surg, Sch Med, Ft Collins, CO USA
来源：
OPERATIVE TECHNIQUES IN SPORTS MEDICINE | 2024年 / 32卷 / 02期
关键词：
orthobiologics; hyaluronic acid; platelet-rich plasma; bone marrow aspirate concentrate; adipose-derived stem cells; microfragmented adipose tissue; amniotic- derived stem cells; PLATELET-RICH PLASMA; MESENCHYMAL STEM-CELLS; MARROW ASPIRATE CONCENTRATE; RANDOMIZED CONTROLLED-TRIAL; ROTATOR CUFF REPAIR; BONE-MARROW; AMNIOTIC MEMBRANE; HYALURONIC-ACID; PLANTAR FASCIITIS; SPORTS-MEDICINE;
D O I：
10.1016/j.otsm.2024.151082
中图分类号：
G8 [体育];
学科分类号：
04 ; 0403 ;
摘要：
Orthobiologics are being investigated to treat a variety of sports medicine pathologies. This article provides an evidence-based approach summarizing currently available options, including viscosupplementation, platelet-rich plasma, bone marrow aspirate concentration, adipose-derived mesenchymal stem cells, and amniotic-derived mesenchymal stem cells. Orthobiologic use in clinical practice necessitates an understanding of the indications, supporting evidence, risks, and benefits. It should maintain a safe, cost-effective, and resourceconscious approach while adhering to regulatory guidelines. This article provides a foundation for understanding when, why, and how to implement orthobiologics. Oper Tech Sports Med 32:151082 (c) 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
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