Complete response of metastatic papillary renal cell carcinoma with inferior vena cava tumor thrombus to nivolumab plus cabozantinib

被引：1

作者：

Hayashida, Michikata ^{[1
]}

Miura, Yuji ^{[2
]}

Yamaguchi, Takeshi ^{[2
]}

Tanaka, Makoto ^{[1
]}

Yamanaka, Taro ^{[2
]}

Takemura, Kohji ^{[2
]}

Oka, Suguru ^{[1
]}

Sakaguchi, Kazushige ^{[1
]}

Ito, Shinji ^{[3
]}

Urakami, Shinji ^{[1
]}

机构：

[1] Toranomon Gen Hosp, Dept Urol, 2-2-2 Toranomon,Minato Ku, Tokyo 1058470, Japan

[2] Toranomon Gen Hosp, Dept Med Oncol, Tokyo, Japan

[3] Toranomon Gen Hosp, Dept Pathol, Tokyo, Japan

来源：

IJU CASE REPORTS | 2023年 / 6卷 / 06期

关键词：

cabozantinib; cytoreductive nephrectomy; inferior vena cava tumor thrombus; metastatic papillary renal cell carcinoma; nivolumab; CYTOREDUCTIVE NEPHRECTOMY; SUNITINIB;

D O I：

10.1002/iju5.12638

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

IntroductionThe effectiveness of nivolumab plus cabozantinib for metastatic papillary renal cell carcinoma with inferior vena cava tumor thrombus remains unclear.Case presentationA 77-year-old male was diagnosed with right papillary renal cell carcinoma with a metastatic lesion on Gerota's fascia, lymph node metastasis, and inferior vena cava tumor thrombus. He was treated with nivolumab plus cabozantinib. As all lesions regressed enough to permit complete resection, radical nephrectomy, thrombectomy, and retroperitoneal lymph node dissection were performed. No viable malignant cells were identified histopathologically. Despite the discontinuation of nivolumab plus cabozantinib, there has been no recurrence for 9 months.ConclusionNivolumab plus cabozantinib has effectiveness for metastatic papillary renal cell carcinoma with inferior vena cava tumor thrombus.

引用

页码：419 / 423

页数：5

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