Study of the Effectiveness of Renshen Yangrong Decoction in Combination with Conventional Drugs in the Treatment of Dilated Cardiomyopathy
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作者:
Meng, Xiangyu
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机构:
Heilongjiang Univ Tradit Chinese Med, Clin Med Coll 1, Dept Tradit Chinese Med, Haerbin 150500, Peoples R ChinaHeilongjiang Univ Tradit Chinese Med, Clin Med Coll 1, Dept Tradit Chinese Med, Haerbin 150500, Peoples R China
Meng, Xiangyu
[1
]
Du, Yue
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机构:
Heilongjiang Univ Tradit Chinese Med, Sch Basic Med, Haerbin 150081, Peoples R ChinaHeilongjiang Univ Tradit Chinese Med, Clin Med Coll 1, Dept Tradit Chinese Med, Haerbin 150500, Peoples R China
Du, Yue
[2
]
Song, Chengjie
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机构:
Daqing Tradit Chinese Med Hosp, Prevent Treatment Ctr, Daqing 163311, Peoples R ChinaHeilongjiang Univ Tradit Chinese Med, Clin Med Coll 1, Dept Tradit Chinese Med, Haerbin 150500, Peoples R China
Song, Chengjie
[3
]
Cui, Zhilin
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Heilongjiang Univ Tradit Chinese Med, Sch Basic Med, Haerbin 150081, Peoples R ChinaHeilongjiang Univ Tradit Chinese Med, Clin Med Coll 1, Dept Tradit Chinese Med, Haerbin 150500, Peoples R China
Cui, Zhilin
[2
]
机构:
[1] Heilongjiang Univ Tradit Chinese Med, Clin Med Coll 1, Dept Tradit Chinese Med, Haerbin 150500, Peoples R China
[2] Heilongjiang Univ Tradit Chinese Med, Sch Basic Med, Haerbin 150081, Peoples R China
[3] Daqing Tradit Chinese Med Hosp, Prevent Treatment Ctr, Daqing 163311, Peoples R China
Dilated cardiomyopathy;
Renshen Yangrong decoction;
cardiac function;
myocardial fibrosis;
ventricular remodeling;
POSITION STATEMENT;
WORKING GROUP;
D O I:
暂无
中图分类号:
R9 [药学];
学科分类号:
1007 ;
摘要:
To investigate the effect of Renshen Yangrong decoction combined with conventional drugs in the treatment of dilated cardiomyopathy. 107 patients with dilated cardiomyopathy were divided into a Chinese medicine group (n=54) and a control group (n=53) using the random number table method. Control group received placebo combined with conventional medication and Chinese medicine group received Renshen Yangrong decoction combined with conventional medication. The clinical efficacy, cardiac function indexes, serological indexes, quality of life scores and adverse effects of the two groups were compared. The overall treatment efficiency of Chinese medicine group was higher than that of control group (p<0.05). After treatment, Chinese medicine group had higher left ventricular ejection fraction, blood volume, serum N -terminal pro -B -type natriuretic peptide, serum procollagen type I carboxy-terminal peptide, serum procollagen type III carboxy-terminal peptide and all Minnesota heart failure quality of life scale scores than control group (p<0.05) and the left ventricular end -diastolic diameter was lower than control group (p<0.05). No adverse events occurred in either group. Renshen Yangrong decoction combined with conventional drugs is safe and effective in the treatment of dilated cardiomyopathy.
机构:
Henan Univ Tradit Chinese Med, Dept Geriatr, Zhengzhou, Peoples R China
Collaborat Innovat Ctr Resp Dis Diag & Treatment, Zhengzhou, Peoples R ChinaHenan Univ Tradit Chinese Med, Dept Geriatr, Zhengzhou, Peoples R China
Li, Jian-sheng
Xie, Yang
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Henan Univ Tradit Chinese Med, Dept Geriatr, Zhengzhou, Peoples R China
Collaborat Innovat Ctr Resp Dis Diag & Treatment, Zhengzhou, Peoples R ChinaHenan Univ Tradit Chinese Med, Dept Geriatr, Zhengzhou, Peoples R China
Xie, Yang
Li, Su-yun
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机构:
Henan Univ Tradit Chinese Med, Affiliated Hosp 1, Dept Resp, Zhengzhou, Peoples R China
Collaborat Innovat Ctr Resp Dis Diag & Treatment, Zhengzhou, Peoples R ChinaHenan Univ Tradit Chinese Med, Dept Geriatr, Zhengzhou, Peoples R China
Li, Su-yun
Yu, Xue-qing
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机构:
Henan Univ Tradit Chinese Med, Affiliated Hosp 1, Dept Resp, Zhengzhou, Peoples R China
Collaborat Innovat Ctr Resp Dis Diag & Treatment, Zhengzhou, Peoples R ChinaHenan Univ Tradit Chinese Med, Dept Geriatr, Zhengzhou, Peoples R China
机构:
St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USASt Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA
Guiguemde, W. Armand
Hunt, Nicholas H.
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机构:
Univ Sydney, Dept Pathol, Sydney, NSW 2006, Australia
Univ Sydney, Bosch Inst, Sydney, NSW 2006, AustraliaSt Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA
Hunt, Nicholas H.
Guo, Jintao
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机构:
Univ Sydney, Dept Pathol, Sydney, NSW 2006, Australia
Univ Sydney, Bosch Inst, Sydney, NSW 2006, AustraliaSt Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA
Guo, Jintao
Marciano, Annael
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St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USASt Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA
Marciano, Annael
Haynes, Richard K.
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North West Univ, Ctr Excellence Pharmaceut Sci, Potchefstroom, South AfricaSt Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA
Haynes, Richard K.
Clark, Julie
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St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USASt Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA
Clark, Julie
Guy, R. Kiplin
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St Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USASt Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA
Guy, R. Kiplin
Golenser, Jacob
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机构:
Univ Sydney, Dept Pathol, Sydney, NSW 2006, Australia
Univ Sydney, Bosch Inst, Sydney, NSW 2006, Australia
Hebrew Univ Jerusalem, Kuvin Ctr Study Infect & Trop Dis, Dept Microbiol & Mol Genet, Jerusalem, IsraelSt Jude Childrens Res Hosp, Dept Chem Biol & Therapeut, Memphis, TN 38105 USA