Simple and green synthesis of 3-acyl-pyrazolo[1,5-a]pyridines: [3+2] through cycloaddition of N-aminopyridines on enaminones

被引：0

作者：

Redon, Sebastien ^{[1
]}

Vanelle, Patrice ^{[1
]}

机构：

[1] Aix Marseille Univ, Inst Chim Radicalaire ICR, Fac Pharm, CNRS UMR 7273,Equipe Pharmaco Chim Radicalaire LPC, 27 Bd Jean Moulin, Marseille, France

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2024年 / 61卷 / 07期

关键词：

DERIVATIVES; ANTAGONISTS; INHIBITORS; DISCOVERY; DESIGN; POTENT; SAR;

D O I：

10.1002/jhet.4851

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A practicable method is described for the synthesis of 3-acyl-pyrazolo[1,5-a]pyridines from N-aminopyridines and easily available enaminones via a [3+2] cycloaddition. The reactions proceed well with a broad scope, without using additive (base or oxidant).

引用

页码：1200 / 1205

页数：6

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