Simple and green synthesis of 3-acyl-pyrazolo[1,5-a]pyridines: [3+2] through cycloaddition of N-aminopyridines on enaminones

被引：0
|
作者：
Redon, Sebastien [1 ]
Vanelle, Patrice [1 ]
机构：
[1] Aix Marseille Univ, Inst Chim Radicalaire ICR, Fac Pharm, CNRS UMR 7273,Equipe Pharmaco Chim Radicalaire LPC, 27 Bd Jean Moulin, Marseille, France
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2024年 / 61卷 / 07期
关键词：
DERIVATIVES; ANTAGONISTS; INHIBITORS; DISCOVERY; DESIGN; POTENT; SAR;
D O I：
10.1002/jhet.4851
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A practicable method is described for the synthesis of 3-acyl-pyrazolo[1,5-a]pyridines from N-aminopyridines and easily available enaminones via a [3+2] cycloaddition. The reactions proceed well with a broad scope, without using additive (base or oxidant).
引用
收藏
页码：1200 / 1205
页数：6
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