Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions

被引：0

作者：

Hajj-Boutros, Guy ^{[1
,2
]}

Faust, Andrea ^{[1
,2
,3
]}

Muscedere, John ^{[4
,5
]}

Kim, Perry ^{[4
]}

Abumrad, Naji ^{[6
]}

Chevalier, Stephanie ^{[7
]}

Aubertin-Leheudre, Mylene ^{[8
]}

Bergman, Howard ^{[3
,9
]}

Bowdish, Dawn ^{[10
]}

Burford, Jessica ^{[11
]}

Carrington-Lawrence, Stacy ^{[12
]}

Cote, Helene ^{[13
]}

Dawe, David E. ^{[14
,15
]}

Barreto, Philipe de Souto ^{[16
]}

Farrelly, Colin ^{[17
]}

Fowler, Robert ^{[18
]}

Gouspillou, Gilles ^{[8
]}

Harrington, Lea ^{[19
]}

Lautrup, Sofie ^{[20
,21
]}

Howlett, Susan ^{[22
]}

Imani, Mahdi ^{[23
,24
]}

Kirkland, James ^{[25
]}

Kuchel, George ^{[26
]}

Mallette, Frederick A. ^{[27
,28
]}

Morais, Jose A. ^{[1
,2
]}

Newman, John C. ^{[29
]}

Pullman, Daryl ^{[30
]}

Sierra, Felipe ^{[31
]}

Van Raamsdonk, Jeremy ^{[32
]}

Watt, Jennifer ^{[18
]}

Rylett, Rebecca Jane ^{[33
]}

Duque, Gustavo ^{[1
,2
,3
]}

机构：

[1] McGill Univ, Dept Med, Montreal, PQ, Canada

[2] McGill Univ, Res Inst, Hlth Ctr, Montreal, PQ, Canada

[3] Schouela Ctr Excellence Sustainable Hlth Sr Schoue, Montreal, PQ, Canada

[4] Canadian Frailty Network, Kingston, ON, Canada

[5] Queens Univ, Dept Crit Care Med, Kingston, ON, Canada

[6] Vanderbilt Univ, Med Ctr, Dept Surg, Div Surg Oncol & Endocrine Surg, Nashville, TN USA

[7] McGill Univ, Sch Human Nutr, Montreal, PQ, Canada

[8] Univ Quebec Montreal, Fac Sci, Dept Sci Act Phys, Montreal, PQ, Canada

[9] McGill Univ, Fac Med & Hlth Sci, Dept Family Med, Montreal, PQ, Canada

[10] McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON, Canada

[11] Western Univ, Fac Hlth Sci, Arthur Labatt Family Sch Nursing, London, ON, Canada

[12] Natl Inst Aging, Div Aging Biol, NIH, Bethesda, MD USA

[13] Univ British Columbia, Dept Pathol & Lab Med, Vancouver, BC, Canada

[14] Univ Manitoba, Max Rady Coll Med, Rady Fac Hlth Sci, Dept Internal Med, Winnipeg, MB, Canada

[15] Paul Albrechtsen Res Inst CancerCare Manitoba, Winnipeg, MB, Canada

[16] INSERM, UMR 1295, CERPOP, Toulouse, France

[17] Queens Univ, Dept Polit Studies, Kingston, ON, Canada

[18] Sunnybrook Hlth Sci Ctr, Dept Crit Care Med, Toronto, ON, Canada

[19] Univ Toronto, Dept Biochem, Toronto, ON, Canada

[20] Univ Oslo, Akershus Univ Hosp, Dept Clin Mol Biol EpiGen, Sykehusveien 25, N-1478 Lorenskog, Norway

[21] Akershus Univ Hosp, Lorenskog, Norway

[22] Dalhousie Univ, Dept Med Geriatr Med, Halifax, NS, Canada

[23] Univ Melbourne, Australian Inst Musculoskeletal Sci AIMSS, Gerosci & Osteosarcopenia Res Program, St Albans, Vic, Australia

[24] Western Hlth, St Albans, Vic, Australia

[25] Mayo Clin, Rochester, MN USA

[26] Univ Connecticut, UConn Ctr Aging, Sch Med, UConn Hlth, Farmington, CT USA

[27] Univ Montreal, Dept Med, Montreal, PQ, Canada

[28] Maisonneuve Rosemont Hosp, Res Ctr, Montreal, PQ, Canada

[29] Buck Inst Res Aging, Novato, CA USA

[30] Mem Univ, Fac Med, St John, NF, Canada

[31] Hevolut Fdn, Riyadh, Saudi Arabia

[32] McGill Univ Hlth Ctr, Res Inst, Montreal, PQ, Canada

[33] Western Univ, Dept Physiol & Pharmacol, London, ON, Canada

来源：

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES | 2024年 / 79卷 / 07期

基金：

加拿大健康研究院;

关键词：

Aging; Animal studies; Clinical trials; Geroscience; Translational Research; CELLULAR SENESCENCE; OLDER-PEOPLE; PROTEIN; CARE; NUTRITION; DISEASE; MUSCLE; CANCER; NUAGE; MEN;

D O I：

10.1093/gerona/glae069

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

The inaugural Canadian Conferences on Translational Geroscience were held as 2 complementary sessions in October and November 2023. The conferences explored the profound interplay between the biology of aging, social determinants of health, the potential societal impact of geroscience, and the maintenance of health in aging individuals. Although topics such as cellular senescence, molecular and genetic determinants of aging, and prevention of chronic disease were addressed, the conferences went on to emphasize practical applications for enhancing older people's quality of life. This article summarizes the proceeding and underscores the synergy between clinical and fundamental studies. Future directions highlight national and global collaborations and the crucial integration of early-career investigators. This work charts a course for a national framework for continued innovation and advancement in translational geroscience in Canada.

引用

页数：9

共 50 条

[21] Navigating the landscape of energy governance: A bibliometric analysis of research trends and future directions
Tabrizian, Hossein
Amiri, Babak
Abdolhamid, Mahdi
[J]. ENERGY REPORTS, 2024, 12 : 2653 - 2675
[22] Interventional Radiology in Canada: Current Challenges and Future Directions
Kennedy, Sean A.
Abraham, Robert J.
Mujoomdar, Amol
Valenti, David A.
Klass, Darren
Wong, Jason K.
[J]. AMERICAN JOURNAL OF ROENTGENOLOGY, 2018, 211 (04) : 736 - 739
[23] Navigating the landscape of concept-supported XAI: Challenges, innovations, and future directions
Khoozani, Zahra Shams
Sabri, Aznul Qalid Md
Seng, Woo Chaw
Seera, Manjeevan
Eg, Kah Yee
[J]. MULTIMEDIA TOOLS AND APPLICATIONS, 2024, 83 (25) : 67147 - 67197
[24] Transient elastography in Canada: Current state and future directions
Aljawad, Mohammed
Sirpal, Sanjeev
Yoshida, Eric M.
Chandok, Natasha
[J]. CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2015, 29 (07) : 373 - 376
[25] The semantic web in translational medicine: current applications and future directions
Machado, Catia M.
Rebholz-Schuhmann, Dietrich
Freitas, Anat.
Couto, Francisco M.
[J]. BRIEFINGS IN BIOINFORMATICS, 2015, 16 (01) : 89 - 103
[26] A Comprehensive Narrative Review on the History, Current Landscape, and Future Directions of Hepatocellular Carcinoma (HCC) Systemic Therapy
Lazzaro, Alexander
Hartshorn, Kevan L.
[J]. CANCERS, 2023, 15 (09)
[27] Current Progress and Future Directions for Theory and Research on Savoring
Bryant, Fred B.
[J]. FRONTIERS IN PSYCHOLOGY, 2021, 12
[28] Myopathy: Recent Progress, Current Therapies, and Future Directions
Andrew L. Mammen
Ricardo H. Roda
Doris G. Leung
[J]. Neurotherapeutics, 2018, 15 : 837 - 839
[29] Genetics and Genomics of Melanoma: Current Progress and Future Directions
Quek, Camelia
[J]. GENES, 2023, 14 (01)
[30] THE HUMAN PLACENTA PROJECT: CURRENT PROGRESS AND FUTURE DIRECTIONS
Weinberg, David H.
Signore, Caroline
Spong, Catherine Y.
[J]. PLACENTA, 2016, 45 : 71 - 71

← 1 2 3 4 5 →